What drugs treat the liver. Hepatoprotectors - drugs for the treatment of the liver, the best drugs, pills. Preparations based on herbal ingredients

Liver diseases in the absence of treatment progress to irreversible, up to coma and death.

Success in treatment is achieved in cases of strict adherence to the doctor's instructions. Not all diseases can be treated until complete recovery.

Preparations for the restoration of liver cells and their functions are prescribed by the attending physician, based on the reasons. When damaged by ethanol, detoxifiers are prescribed, viruses - antiviral, bacteria - antibiotics.

Preparations are produced with herbal extracts and with synthetic components, combined and single-component.

This group is characterized by pharmacological properties:

• increased activity of enzyme systems of the body;
• strengthening detoxification ;
• stabilization of cell functions;
• protection of cell membranes;
• stimulation of hepatocyte recovery.

In the therapy system, auxiliary groups are prescribed to eliminate the causes:

• antibiotics (with);
• immunomodulators (with viral etiology);
• antispasmodics (with);
• antitumor (for malignant neoplasms);
• antioxidants;
• parenteral nutrition with amino acids.

List of effective drugs

Active ingredients of hepatoprotectors:

• glycyrrhizic acid;
• bicyclol;
• glutathione;
• arginine glutamate;
• ursodeoxycholic acid;
• inosine;
• lecithin;
• methionine;
• thiotriazoline;
• essential phospholipids;
• milk thistle;
• ademetionine.

List of drugs for the liver with glycyrrhizin in the composition:

• Phosphogliv, ;
• Essentialgliv.

Trade names with ademethionine as the active substance:

• Heparetta;
• Heptrazan;
• Sameliks.

With glutathione, one medication is released - Glation. With arginine glutamate drugs - Glutargin, Glutargin Alkoklin.

Names of medicines with ursodeoxycholic acid:

• Livodex;
• Ursodex;
• Ursoliv;
• Ursolite;
• Ursomic;
• Ursor Rompharm;
• Choludexan;
• Ekurochol.

On the basis of inosine - Inosie-F, lecithin - Livolife Forte, methionine - the drug of the same name from various pharmaceutical plants, thiotriazoline - the same name of Ukrainian production.

Medicines are produced with essential phospholipids:

• , Essentiale Forte N;
• Rezalut Pro;
• Antraliv;
• Livenziale;
• Phosfonciale;
• Esslial Forte;
• Eslidin;

List of herbal preparations in the form of milk thistle (silymarin) for the treatment and improvement of liver function:

• Karsil;
• Silibinin;
• Silimar;
• Forliver Help;
• Gepabene;
• Hepaphor;
• Sibektan.

Other means:

• Metadoxil;
• Hepa-Merz;
• Livolin;
• Progepar;
• Remaxol;
• Liv-52;
• Neohep;
• Maksar;
• Flamin;
• Molixan;
• Laennec.

The most effective drugs for the treatment of liver diseases, based on the ratio of a positive result from taking and a mild effect on the body, consumers consider: Essliver Forte, Essentiale Forte N, Phosfonciale.

Inexpensive medicines for organ restoration

A range of low-priced products to improve liver function:

• Lipoic acid (protects cells, removes toxins);
• Allohol (accelerates the secretory function);
• Methionine (relieves intoxication, increases the production of phospholipids).

Inexpensive and effective hepatoprotective drugs:

• Silimar (based on milk thistle);
• (with flowers of sand immortelle, promotes regeneration, enhances the secretion of bile and promotes its outflow);
• Hepaphor (lacto- and bifidobacteria with milk thistle);
• Phosfonciale (to protect the structure of hepatocytes and improve liver function);
• Legalon (accelerates regeneration, protects against toxic substances);
• Tykveol (restores, stimulates the production of hepatocytes);
• Liv-52 (stimulates tissue repair, protects against damaging toxins);
• Hofitol (based on artichoke extract);
• (with milk thistle in the composition);
• Gepabene (herbal remedy, restores hepatocytes);
• Livolin (combined vitamin medication).

Liver disease

The best hepatoprotective phospholipids to protect hepatocytes

The main component of this group of drugs is esters of polyhydric alcohols, elements of physiological membranes that are synthesized in the liver. Phosphatidylcholine - the active component of phospholipids stimulates the process of self-reconstruction of the organ, protects hepatocytes from poisons, aggressive substances and their decay products, participates in molecular transport.

Medicines are released with one active ingredient and in combination with others to enhance the therapeutic effect in liver diseases. Auxiliary components - vitamins, glycyrrhizic acid, silymarin, methionine.

Hepatoprotective drugs with a monocomponent composition:

• Antraliv;
• Esslial Forte;
• (solution in ampoules);
• Phosfonciale Mono;
• Livenziale;
• L'Esfal;

Methods of administration depend on the dosage form: enteral (oral) and parenteral (intravenous).

Dosage and duration of liver medications is determined by the attending physician based on the history and examination results.

Essliver Forte is a combined remedy supplemented with a vitamin complex.

Auxiliary substances enhance the main component and act as:

• regulator of carbohydrate metabolism, protein production;
• catalysts for saturating cells with oxygen;
• participate in the metabolism of amino acids, nucleotides;
• protection from free oxygen.

Eslidine is a combined agent with phospholipids and methionine. Substances react by acting as a catalyst for each other.

The action of the complementary component methionine is aimed at:

• increases the production of choline;
• reduces the number of fat cells in the body;
• neutralizes xenobiotics;
• reduces the level of bad cholesterol;
• regulates carbohydrate, fat and protein metabolism;
• regulates the synthesis of hormones and vitamins.

Phosfonciale - phospholipids with milk thistle extract as active substances. The action of silibinin (the most active component of silymarin) is aimed at stimulating the discharge of bile, and helps protect the structure of hepatocytes.

Medicines for the liver with an additional active ingredient in the form of sodium glycyrrhizinate (trisodium salt of glycyrrhizic acid): Phosphogliv, Essencigliv. Essential components improve the properties of glycyrate (glycyrrhizic acid and salts), accelerate its absorption.

Properties of glycyrrhizic acid:

• antiviral;
• immunomodulatory;
• anti-inflammatory;
• membrane stabilizing;
• hepatoprotective;
• antiallergic;
• antioxidant.

Doctors consider the best drugs for the treatment of hepatic diseases to be combined drugs of multidirectional action.

Medicines for the treatment of cirrhosis

The disease is more often diagnosed after 40 years, the ratio of sick men and women is 3:1. - a pathological condition, which is characterized by the death of hepatocytes, cell restructuring with the formation of a dense functional tissue instead of healthy cells and nodes. Subsequently, it develops into and.

A dangerous complication of cirrhosis is (brain damage by toxins), the extreme degree of which is coma (unconsciousness). The sooner measures are taken to preserve healthy liver cells, the more favorable the outcome.

Etiology of cirrhosis development:

• inflammation caused by viruses;
• autoimmune diseases;
• alcoholism;
• metabolic disorders;
• violation of the patency of the bile duct;
• veno-occlusive disease;
• damage by toxins, drugs.

Hepa-Merz is a synthetic agent prescribed during the acute or chronic stage with hyperammonemia, with impaired brain function due to hepatic dysfunction.

Pharmacological properties:

• detoxification;
• reduces ammonia levels;
• stabilizes protein metabolism.

Hepatosan is a drug for the treatment of cirrhosis based on freeze-dried pig liver cells. It is recommended when the body is exposed to poisons, medicines and ethanol because of the ability to remove them from the body.

Karsil is a herbal remedy for oral administration with silymarin in the composition.

Apply when:

• cirrhosis;
• toxic lesions;
• poisoning;
• liver injuries.

Pharmacological properties:

• protects against oxidation;
• restores the processes of self-regeneration;
• removes toxins.

Liv-52 is a phytopreparation with a multicomponent composition.

Incoming herbs and extracts determine its main properties:

• stabilizes cell membranes;
• restores hepatocytes and their work;
• stimulates the synthesis of phospholipids;
• reduces degenerative changes in liver tissues;
• regulates intracellular processes;
• neutralizes the oxidative action of free radicals;
• neutralizes and removes toxins, poisons;
• eliminates inflammatory processes;
• stimulates the excretion of ethanol and its decay products.

Livolife Forte is a lecithin-based drug containing phosphatidylcholine. Restores cells and basic functions of the body.

Assign when:

• change in the structure of the body;
• inflammation during infection with viral agents;
• lesions with ethanol, medicines, poisons, heavy metals;
• dystrophic rebirths;
• coma due to violations of the liver;
• preeclampsia.

Livolin Forte is a multicomponent drug made from soybean lecithin, supplemented with a vitamin complex. Pharmacological properties are typical for the group of phospholipids.

Prohepar is a multicomponent hepatoprotective drug.

Operates in the following directions:

• stimulates the regeneration of the damaged part of the parenchyma;
• maintaining a stable blood flow in the tissues;
• restores the structure of hepatocytes.

Rezalut Pro - effective drug for the treatment of the liver based on soy phospholipids.

Pharmacological properties:

• promotes regeneration;
• protects against oxidation;
• improves the metabolism of fat-like compounds and alcohols;
• lowers cholesterol levels.

Sibektan - a mixture of substances of natural origin, stabilizes the state of the parenchyma, protects against oxidation.

Silimar is a phytomedicine with the same name component.

Herbal remedy with oil as an active ingredient.

Pharmacological properties:

• antioxidant;
• reconstructs liver membranes and improves their properties;
• anti-inflammatory;
• choleretic;
• removes toxins.

Phosphogliv, Essentiale Forte N, Essliver are medicines of the phospholipid class with typical properties.

Hofitol is a phytopreparation with a dry extract of artichoke leaves. Assign as an aid in the stagnation of bile.

Eslidine is a two-component medicine with polyunsaturated soy lecithin and methionine. It is indicated for complicated conditions after exposure to poisons, toxins, medicines on the liver to restore its cells.

Medicines with ademetionine (Heparetta, Heptor, Heptral) work in the following areas:

• stimulation of the production of phosphatidylcholine;
• improves the biochemical parameters of organs;
• removes toxins;
• promotes regeneration.

Geptrong - honey, converted for parenteral use (intramuscularly). Shown as an aid in case of liver damage by aggressive substances (poisons, medicines, heavy metals).

Glathion is a detoxifying drug with glutathione. Indicated for use in liver damage by alcohol, toxins, drugs.

Glutargin is a hepatic drug with arginine glutamate.

Hepatoprotector with pharmacological actions:

• activates the processes of neutralization of ammonia and promotes its removal;
• stabilizes energy supply in hepatocytes;
• slows down oxidative reactions.

Inosie-F is the active substance inosine. Metabolic agent that reduces tissue hypoxia to maintain normal liver functions.

Livenziale is a phospholipid-based drug in the form of a parenteral form to improve the functioning of the organ.

Drugs with ursodeoxycholic acid (Livodex, Urdox, Ursodez) are prescribed for the treatment of the liver in the first stages of cirrhosis.

Maksar is a hepatoprotector based on the wood extract of the Amur maakia.

Pharmacological characteristics:

• restoration of the respiratory function of cells;
• stabilization of the secretory abilities of the liver;
• reduces the number of necrotic hepatocytes;
• prevents the damaging effects of free radicals on living cells.

Methionine is a metabolic agent that reduces deposits of free fat in the liver, regulates the production of vitamins and hormones in the body.

Ornilatex - a drug based on ornithine aspartate, restores protein metabolism. Indicated in severe cirrhosis, including coma.

Pyrogenal is an immunostimulating drug of bacterial origin. It is used in cases of viral damage, with long-term degenerative chronic processes in the liver.

Ropren is a herbal preparation for the treatment of the liver, based on a product of processing woody greens of European spruce.

Phytochemical actions:

• stabilizes cellular metabolism;
• restores hepatocytes;
• promotes the elimination of toxins.

Thiotriazoline is an antioxidant that promotes regeneration, stabilizes metabolic processes.

Laennec - injection solution from hydrolyzed human placenta. Shown with, organ. Activates metabolic activity, humoral immunity.

Neohep is the main substance 1-violuric acid. Eliminates dystrophic changes in the liver parenchyma, inflammatory processes.

Metadoxil is the active substance metadoxine, a derivative of pyridoxine.

Drug for the treatment of alcohol dependence with pharmacological properties:

• removes ethanol and its decay products;
• reduces cravings for alcohol;
• protection of the liver from the action of ethyl alcohol;
• restores the ratio of fatty acids;
• reduces the risk of developing cirrhosis.

Any drug must be prescribed by a doctor

Preparations with silymarin in the composition contain flavolignans, which determine its pharmacological properties:

• strengthen cell membranes;
• retain enzymes;
• protect cells from exposure to reactive oxygen species;
• stimulate bile secretion.

Indications for use:

• conditions after viral or toxic hepatitis;
• cirrhosis;
• intoxication with poisons, drugs.

List of herbal preparations with milk thistle in the composition for the stabilization of liver functions:

• Karsil;
• Legalon;
• Silybin;
• Silimar;
• Forliver Forte;
• Gepabene;
• Hepaphor;
• Sibektan.

The best herbal preparations, according to consumers, from the ratio of effectiveness from administration and softness of action: Legalon, Silimar, Karsil.

What helps with hepatitis?

Unstable work of cells and - indications for an integrated approach. The basis of liver treatment for hepatosis is drugs to restore and protect hepatocytes.

Groups of drugs for hepatosis:

• hypoglycemic agents (Metformin, Siofor);
• reducing the concentration of harmful sterols (Atorvastatin, Clofibrate);
• antioxidants (Mexidol, vitamins A, E, C);
• antihypoxants (Carnitine, Actovegin, Trimetazidine).

What else needs to be done to restore liver cells?

For recovery, it is necessary to change lifestyle and gastronomic habits. Diet and proper healthy eating stabilizes the work of the whole organism, normalizes weight, reduces the amount of fat in the liver.

When drawing up a nutrition plan, the following conditions are observed:

• observe the drinking regimen from 1.5 to 2 liters per day of water;
• plan a menu based on the needs of the body - the norm of proteins (100-120 g), fats (80 g) and carbohydrates (250-320 g);
• restriction of salt (no more than 8 g per day) and sugar;
• sources of fat vegetable oils in more part than animals;
• meals 6 times a day;
• average serving temperature;
• remove fried foods from the diet, prefer steamed, stewed;
• exclude pickles, spices, spicy;
• do not stretch the walls of the stomach by overeating;
• do not take alcohol;
• exclude coffee, cocoa from drinks.

In severe liver failure, including coma and encephalopathy, parenteral nutrition is indicated with solutions of amino acids - Aminoplasmal Hepa, Hepasol-Neo.

Useful video

The video will tell you about what liver diseases are and how to deal with them:

Conclusion

What drugs to treat the liver - only the attending physician determines after collecting anamnesis and research. With self-selection medicines there is a risk of doing more harm than good.

Herbal remedies have a minimum number of side effects, are prescribed for prevention. Among the shortcomings, low efficiency is noted in the treatment of acute hepatitis and alcoholic liver damage.

Benefits of treatment with phospholipid-based drugs:

• well tolerated;
• quickly digested;
• improve enzymatic activity;
• some are allowed for pregnant women.

Disadvantages of this group:

• high price;
• the risk of developing inflammation;
• long course of 6 months.

When choosing medicines, one should analyze not only the ratio of advantages and disadvantages, but also doctor's recommendations, concomitant diseases.

If therapy in the first stages was started in a timely manner, the prognosis is favorable. Self-medication for violations of the liver is unacceptable and leads to disastrous consequences.

Hello dear readers. Lifestyle, working conditions, the state of the environment - all this is far from ideal, which cannot but affect the state of health. Unfortunately, few people think about it at a young age. And over time, damage to various internal organs, accumulating, lead to malfunctions in the body. The liver is severely affected. The question of her cure is quite acute today for many people. This article will discuss various pills for the liver - a list, hepatoprotectors that restore the liver, their positive aspects and disadvantages.

Reasons for the development of liver pathologies

The liver is a multifunctional organ.

It is responsible for such important functions as:

✔ Filtration of toxins.

✔ Transformation of vitamins and minerals into a form available to the body.

✔ Participation in digestion, splitting of lipid structures.

✔ Regulation of hormonal levels and metabolism.

✔ Hematopoiesis, control of blood composition and coagulability.

✔ Creation of means for immune protection.

Failures in the work of this organ immediately negatively affect the state of the whole organism. The liver is already experiencing tremendous stress, and here also various factors constantly interfere with its normal functioning.

1. Excess weight.

1. Addiction to alcohol, drugs, smoking.

1. Irrational nutrition.

1. Environmental pollution.

1. The use of medicines.

1. congenital abnormalities.

1. Diabetes, foci of infections, pancreatitis, gallbladder damage.

1. Physical inactivity.

How to help the liver

Various groups of pharmacological preparations are aimed at combating the consequences of such a negative impact and protecting the liver structures.

Their use depends on the type of pathology:

✔ Cholagogue - activate the gallbladder, improve the breakdown of fatty foods.

✔ Hepatoprotectors - protect the liver from destruction, promote its regeneration.

✔ Antiviral - necessary in the presence of a viral lesion of the organ.

Hepatoprotectors that restore the liver are in the greatest demand. The liver has an amazing ability - in the presence of optimal conditions, it is able to self-repair in a short time.

This is possible even after mechanical removal a significant part of it. Hepatoprotectors also help to cope with this task with the greatest efficiency. They remove part of the load from it, cleanse it, activate the appearance of new cells.

But all this is possible only under the condition of strict adherence to the diet (you need to normalize weight and provide the body with the necessary "building materials"), eradicate bad habits, and cure concomitant diseases of the digestive system.

Hepatoprotective agents are divided into several drug groups. The division occurs depending on the active components contained in them.

1. Based on vegetable raw materials. These include medicines, dietary supplements, herbal teas. They are widely used in different situations: with hepatitis, gallbladder damage, the appearance of stones, intoxications of various etiologies, as well as for the purpose of preventive action. They may include such medicinal plants as milk thistle, chicory, artichoke, burdock, elecampane, yarrow, fume, pumpkin, etc. These can be tablets, capsules, tinctures, herbal teas. Examples of drugs: hepabene, silimar, darsil, hofitol, tykveol.

1. Based on extracts from the liver of animals. They contain natural regeneration activators. Made from pork and beef liver. Powder products and capsules are available for sale. Medicines are dispensed by prescription, as they have many contraindications. Examples: hepatosan, prohepar.

1. Phospholipid. They play the role of those very “building materials” for the liver, due to which damaged cells are restored. They are of plant origin. Pharmacies sell sachets, tablets and capsules. Examples: Essentiale, phosphonciale (brenciale, lipostabil, phosphogliv, essliver forte), hepaguard.

1. Amino acids. They take part in the synthesis of phospholipids and active substances, participate in the mechanisms of liver cleansing. They are prescribed for poisoning, chronic hepatitis, alcoholism, dystrophic pathologies. Sold by prescription. Examples: ornitox, heptral (heptor).

1. Homeopathic. Cleanse the liver, contribute to the restoration of its work. Examples: galstena, hepel.

1. Contains bile acids. Stimulate the production of digestive enzymes, have an immunostimulating and choleretic effect, reduce sugar. They are prescribed by a doctor. Examples: ursosan (ursofalk, ursohol, destolite), urdox, livodex.

It should be noted that in many countries hepatoprotective agents are not recognized as drugs, but are classified as dietary supplements. Their effectiveness has not been confirmed in clinical trials. Although there is no particular confidence in such studies.

This is an expensive procedure, paid for by pharmaceutical companies, with pre-planned results. Some studies of domestic medicine are fundamentally different from Western ones.

When to use hepatoprotectors

Preparations, including dietary supplements, should be prescribed by a specialist. Indications for use are as follows:

- alcoholism, the likelihood of developing cirrhosis;

- fatty degeneration (steatosis) - the parenchyma is replaced by adipose tissue, the pathology is characteristic of obesity and diabetes, if this is a consequence of alcoholism, hepatoprotectors are not prescribed;

- secondary treatment of viral lesions - carried out after a course of antiviral therapy in case of its failure;

- poisoning, primary cirrhosis of a cholestatic nature - you need to follow a diet;

- prevention of poisoning due to the peculiarities of professional activity, living in areas with poor ecology.

Medicines for the liver - herbal preparations are inexpensive and effective

There are many inexpensive herbal liver medicines that help restore the liver and gallbladder.

1. Based on Tatarnik (milk thistle). It is considered to be the best among hepatoprotective agents. A mixture of the active components of the plant, called silymarin, has a powerful cleansing and antioxidant effect. The negative points include the need for a very long reception (at least three months) to obtain therapeutic effect and instructions in the instructions for insufficient dosage to eliminate serious intoxication (70 mg is only suitable for prophylactic effects on the liver). Recommended drugs:

✔ Karsil (darsil, levasil, silibor).

✔ Silimar.

✔ Silarin.

1. Artichoke based. The active compound here is cynarin (an analogue of silymarin in a Tatar). In addition to protecting the liver, it helps with joint pain, lowers cholesterol, has a diuretic effect, and stimulates the work of the gallbladder. It is not recommended to use these funds in the presence of obstruction of the bile ducts, cholelithiasis, inflammation. The drug is hofitol. And from dietary supplements, you can advise taking cynarix or artichoke extract.

1. Combined dietary supplements. These compounds have a choleretic, protective, regenerative effect and stimulate protein synthesis. Their effectiveness is partially confirmed by studies of domestic physicians. But there is not enough data to recognize these drugs as medicines. Examples: liv 52, milona, ​​ovesol, hepatotransit.

1. Pumpkin seed oil. Contains fatty acids, vitamins, tocopherols, hepatoprotective phospholipids. The oil is part of tekveol and peponen.

Medicines of animal origin

Means are prescribed exclusively by a doctor. They help restore hepatic structures, inhibit the processes of replacing the parenchyma with connective tissue, and are diuretics, which helps to cleanse the body. May cause allergies, are not used for exacerbation of hepatitis.

✔ Prohepar.

✔ Hepatosan.

✔ Sirepar.

Amino acids

These drugs activate the production of biologically active substances, which determines their protective and regenerative function.

They remove fats from hepatocytes, act as antidepressants and antioxidants, and are effective for cirrhosis, intoxication, and bile problems. The doctor may prescribe a heptor or heptral.

Phospholipid preparations

These funds can be prescribed when a patient is diagnosed with:

- fatty infiltration;

- hepatitis of various origins;

- cirrhosis;

- Radiation disease.

The so-called essential phospholipids, integrating into the walls of damaged cells, restore their original structure. This allows the renewed hepatocytes to function fully.

They become more powerful and able to resist all sorts of negative influences. It is in the supply of such substances that the action of this group of drugs lies.

But that's in theory. As a number of studies have shown, in fact, these compounds simply do not enter the liver in the right form - even before that, most of them are broken down during digestion.

Moreover, these drugs can provoke stagnation in the bile and contribute to the development of inflammation. And all this with a sufficient high cost of the drugs in question.

Examples of drugs are shown below.

1. Essentiale forte N. Natural remedy, well tolerated by patients. It can be used for prevention and in the complex treatment of a number of non-hepatic diseases (psoriasis, radiation exposure, etc.). Used during pregnancy. May cause allergic manifestations, diarrhea.

1. Phosphogliv (phosphonciale). The combined drug has anti-inflammatory and hepatoprotective effects. The capsules are taken with food and should not be chewed. Can cause a jump in pressure, allergies, swelling.

bile acids

This group of drugs, when taken, is responsible for lowering cholesterol, regulating sugars, enhancing the production of digestive juices and bile, and activating immune responses.

The funds are also effective in severe forms of liver and gallbladder damage. They are prescribed even to teenagers and pregnant women. But they also have many contraindications. Names of drugs: ursochol, ursofalk, ursodeoxycholic acid.

homeopathic remedies

Considered to be quite effective. Eliminate symptoms, contribute to a significant improvement in the general condition.

But you need to take drugs for a long time. They are not recognized by official medicine.

✔ Hepel.

✔ Milk thistle.

How to choose a hepatoprotective agent

If there are any signs of liver damage, you should immediately seek medical help. All appointments are made by a doctor. Even the intake of non-drugs (biologically active supplements, homeopathic formulations), including for prevention, should be discussed with a specialist - gastroenterologist, naturopath, homeopath.

It should be remembered that under certain conditions and pathologies, hepatoprotectors cannot be taken. In addition, products of animal origin and polycomponent plant mixtures, for example, Chinese herbs, have a certain danger.

First, they have not been clinically tested. Secondly, their active ingredients can increase the concentration of toxins dangerous for the liver, and not get rid of them.

Preparations for children

Already in childhood, serious problems with the liver can be observed. Many hepatoprotective agents are not suitable for children.

Based on the overall picture, a specialist can prescribe treatment:

✔ Galstenoy;

✔ Darsilom;

✔ Hepel;

✔ Essentiale.

✔ Urosan.

Drugs to restore the liver with alcohol intoxication

The consequences of serious poisoning with alcohol-containing drinks are eliminated by medication. The effectiveness of the course is possible only if the patient completely refuses alcohol. Not all of the above funds can be used, so the help of a physician is needed.

There is a high risk of aggravating the situation if you self-medicate and randomly take dietary supplements. Preparations made from plant materials have proven themselves well - with milk thistle, elecampane, burdock root, etc.

With obesity

In the presence of excess weight, taking drugs should be accompanied by the use of pharmacy vitamins and diet food. Various groups of medicines can be prescribed - both of plant and animal origin, as well as with phospholipids, bile acids. In this case, dietary supplements and homeopathic remedies are widely used.

Hepatoprotectors to eliminate the consequences of taking medications

In the presence of drug intoxication, as in the case of its likelihood, hepatoprotectors are prescribed. Since they can cause additional overload of the liver, only those drugs are selected that have the fewest contraindications and a powerful cleansing effect.

Cirrhosis of the liver and hepatoprotectors

A well-designed treatment regimen will protect hepatocytes from the destructive effects of toxins, stop the process of replacing parenchymal tissue with fibrous tissue, and restore the functionality of the organ.

But for this it is necessary not only to resort to hepatoprotectors, but also to change the diet, take vitamin complexes. It is important to follow the doctor's instructions, avoid provoking factors and monitor the patient's condition.

Taking medicines for hepatitis

Treatment for hepatitis depends on its type. Here we need an integrated approach and taking into account the characteristics of the body's response to therapeutic measures.

More often, hepatoprotectors are used as auxiliary drugs and as a secondary drug effect.

general doctor.

Scientists call the liver the "chemical laboratory" of the body. All useful and toxic components pass through the gland. For some time, the body is able to function under conditions of increased load, and then the working resource is depleted, which leads to a malfunction.

The load on the liver increases against the background of the abuse of alcoholic beverages, when taking drugs for a long time or in high dosage. Diet also has a negative effect on the state of the liver. Consumption of spicy, fatty and smoked foods disrupts the functioning of the body.

How to protect and how to support the liver when taking medications, which drugs will restore the functionality of the organ, prevent complications - we will consider in detail.

Hepatoprotectors to protect the liver

Against the background of problems with the functionality of the liver, doctors prescribe hepatoprotectors. This is a group of drugs that is always included in the treatment regimen for hepatitis C, toxic and alcoholic nature. Recommend reception during long-term treatment with antibiotics, antitumor agents.

The range of hepatoprotectors is huge. All drugs differ in active ingredients, nature of origin, indications, cost. Not all medicines are equally good, so patients are looking for medicines with proven effectiveness.

How to protect your liver while taking medication? For this purpose, protective drugs are used. Doctors use the classification of hepatoprotectors:

Medicine group	Description	Name of drugs
Phospholipids essential	They are distinguished by high cost and ultimate effectiveness in the treatment of various liver pathologies. They restore liver cells, improve the properties of bile. To achieve the desired result, the course is long - at least 6 months. The best effect is manifested when not pills are prescribed, but injections (done intravenously).	Essentiale N, Essentiale Forte N, Phosphogliv, Rezalyut
Animal products	They help against the background of cirrhosis, fatty hepatosis, hepatitis of any genesis. The basis of the drug is porcine liver cells. Properties - normalize blood circulation in the gland, restore the full structure of the liver cells, inhibit the formation of blood clots, improve functionality. The disadvantage is the lack of clinical studies confirming the claimed result of therapy.	Hepatosan, Progepar
Amino acids	They break down lipids, remove them from the gland, that is, they help cleanse the organ. In the course of clinical studies, the effectiveness of the substance ademetionine, which is in the composition, has been proven. Amino acids are triple protection hepatoprotectors with good reviews from doctors.	Heptral, Heptor, Hepa-Merz (Ornithine aspartate)
Herbal medicines	Preparations of this group have few contraindications, rarely lead to the development of negative phenomena. They are used in the treatment of diseases of the liver, biliary tract, gallbladder and other pathologies of the gastrointestinal tract. The release form is different - powder, oils, tablets.	Silimar, Karsil
dietary supplements	You can support the liver with the help of dietary supplements. As a rule, they have many different plants in their composition. However, they are not a drug, which should be taken into account.	Artichoke extract, Liv 52, Hofitol
Bile acids	Ursodeoxycholic acid (abbreviated as UDCA) is a bile acid preparation. Used for pathologies of the liver, gallbladder.	Ursofalk, Urosliv, Ursosan
Homeopathic preparations	Good reviews are left by patients for this subgroup of drugs. Homeopaths claim that tablets / drops / solutions quickly stop negative symptoms, accelerate regeneration processes in the liver, and restore cells. Minus - the drugs in this group have not undergone clinical trials, so talking about 100% effectiveness is impractical.	Galstena, Hepel

All these drugs will help protect the liver from negative effects. It is difficult to say which remedy is better, because the effect depends on the initial disease, general condition, diet during therapy.

When are hepatoprotectors used?

Liver protection is necessary when taking hormonal, antibacterial drugs for a long period; during chemotherapy; with a number of diseases of the gland, which can worsen, lead to serious illnesses.

To reduce the degree of negative impact on the liver, help in recovery, hepatoprotectors are prescribed:

1. In the viral form of hepatitis, when antiviral tablets cannot be used due to contraindications or they do not help. Assign only after a blood test by ELISA, which determines the presence of antibodies in the blood. That is, cells that produce immunity in response to antigens.
2. When, when the likelihood of developing cirrhosis is high. It is possible to restore the organ if the patient completely refuses feasts with alcoholic beverages.
3. For the treatment of fatty liver. They are used only in combination, diet, physical activity, lowering cholesterol levels are additionally recommended.
4. With drug-induced cirrhosis.

Hepatoprotectors work only in combination with proper nutrition, refusal of alcoholic beverages.

Medicines to protect the liver while taking medications

So how can you protect your liver? This can be done with the right lifestyle, medications and folk remedies. The latter option is best combined with medications and only after consulting a doctor. Consider a list of drugs that help improve liver function.

Tykveol

There are three forms of release - capsules, oil for internal use and suppositories for rectal administration. Capsules are drunk 30 minutes before a meal. The dosage is 1-2 pieces, the frequency of use is 3 times a day. The dose of oil is a teaspoon, the multiplicity is up to four times a day. The duration of treatment is determined individually, but not more than 2 months.

Advantages of the drug:

• Plant nature.
• No side effects.
• It goes well with other medicines.
• Proven efficacy in clinical studies.
• Contains vitamins.

In the treatment of liver pathologies, Tykveol cannot be used as a single drug. In case of hypersensitivity, an analogue is selected. The cost depends on the form of release, varies from 305 to 470 rubles.

Hepa-Merz

Hepa-Merz - full protection of the liver when taking medications. The drug eliminates the symptoms of intoxication, reduces the concentration of ammonia in the blood, and gives an analgesic effect. It also normalizes metabolic processes, eliminates dyspeptic manifestations. The therapeutic result is manifested due to ornithine aspartate - the active ingredient.

Hepa-Merz prevents the destruction of hepatocytes, accelerates regeneration processes, and is used in the treatment of acute and chronic liver pathologies.

Advantages:

1. Quickly relieves the symptoms of drug, alcohol poisoning.
2. Helps with liver diseases, regardless of pathogenesis.
3. Restores body cells.

The disadvantages include the presence of contraindications - pregnancy, lactation, renal failure in the patient. The medicine can provoke an allergy. The price is high - from 800 rubles.

Ursofalk

How to protect the liver when taking various drugs for a long time? For this purpose, the use of Ursofalk is recommended.

It provides a choleretic effect, dissolves cholesterol stones, protects the liver. Ursodeoxycholic acid is an active biological component. Reception is carried out under medical supervision, the determination of indicators of liver tests is constantly required.

Main advantage - Ursofalk activates immune system a patient with a lasting effect of regeneration of damaged hepatocytes.

Cons - there are contraindications (acute inflammation of the bile ducts, tuberculosis, gallbladder empyema, etc.), side effects in the form of allergies, dyspeptic manifestations. The price of 50 capsules of 250 mg is 930 rubles.

Hofitol

Vegetable medicinal product protecting the liver. It has a choleretic and diuretic effect, lowers blood pressure. As part of artichoke extract dry (tablets) or water (solution).

Application advantages:

• It is combined with any medicines without reducing the therapeutic effect.
• Thanks to vegetable nature well tolerated.
• Can be taken for a long time.
• Under the supervision of a doctor, it is possible to treat pregnant women.

Cons - side effects that develop in about 20% of patients. Patients complain of diarrhea, headache, severe itching of the skin.

Karsil

The medicine helps to restore the functionality of the liver, prevents pathological transformations in the liver cells. Contains milk thistle extract.

Pros of using:

1. It is used in the treatment of hepatitis, steatosis, cirrhosis, which are accompanied by weight loss, metabolic disorders.
2. It can be used as a prophylaxis of liver damage against the background of prolonged use of antibiotics and other drugs that have a hepatotoxic effect.
3. Adverse events in patients are rare.

Pregnant and lactating women should not be treated. The simultaneous use of Karsil with oral contraceptives is not recommended, since the effectiveness of the latter decreases. The price is 350 rubles.

Essentiale Forte

Relatively inexpensive drug with a unique composition.

Essential phospholipids are built into the structure of liver cells, have a restorative effect, normalize the metabolism of fats and proteins, and reduce the rate of replacement of hepatocytes with connective tissue.

Advantages:

• Contains only natural ingredients.
• High therapeutic effect in pathologies that are characterized by the rapid destruction of liver cells.
• Can be used during pregnancy, breastfeeding.
• As a prophylaxis, it is prescribed at the risk of the formation of stones in the gallbladder.
• Prevention of stroke, heart attack, atherosclerotic changes in blood vessels.
• The medicine normalizes the digestive tract.

Against the background of prolonged use, an allergic reaction, pain in the epigastric region, nausea, and diarrhea may occur.

Phosphogliv

Combined hepatoprotector with additional antiviral and immunomodulatory effects.

The instruction indicates that the agent improves liver function, inhibits the activity of viral pathogens, and stimulates the synthesis of its own interferons.

Advantages of Phosphogliv:

1. Well tolerated, adverse reactions are rare.
2. The unique composition and a wide range of therapeutic effects allow it to be used for liver pathologies of any etiology, of varying severity.

Homeopathic medicines for liver restoration

Good reviews have homeopathic tablets Hepel and Galsten. Consider the drugs in more detail in the table:

Name	Description
Hepel	The medicine has a wide spectrum of action. Gives anti-inflammatory, antispasmodic and hepatoprotective effect, normalizes the digestive tract. Tablets help with liver pathologies of inflammatory and toxic origin. Take 3 tablets every day, the course lasts individually. Do not use in the treatment of pregnant women during lactation. The cost of 50 tablets is 350 rubles.
Galstena	Available in the form of drops and tablets. Complex drug with hepatoprotective properties. Reduces the severity of intrahepatic cholestasis, cytolysis syndrome, relieves dyspeptic manifestations. Assign for diseases of the liver of acute and chronic course, gallbladder, pancreas. It is forbidden to use for alcohol dependence, organic intolerance to the composition.

Recovery from alcohol

Recovery of the liver after alcohol involves the process of cleansing the liver after a single use or alcohol dependence. In the first case it is enough drinking regime, sparing diet, do not use tablets. In alcoholism, the choice of drugs is determined by the degree of damage to the gland.

Coopers Neo

Dietary supplement with natural ingredients. It comes in the form of capsules that dissolve in the intestines. BAA has a positive effect not only on the liver, but also on other organs - the kidneys, intestines, heart.

Coopers Neo fits the outflow of bile, stimulates the gallbladder. The active substances in the composition reduce the concentration of fats in bile. To others medicinal properties include regulation of enzyme activity, normalization of digestion.

Accepted within 2-3 months. The dosage for an adult is 2 capsules every 8 hours. Improvements appear after 20 days of treatment. If there is a history of stones in the lumen of the bile ducts, the supplement is prohibited for use. During treatment, alcohol is prohibited.

Deepana

Herbal hepatoprotective drug. Produced in tablet form.

Contains extracts of medicinal plants.

The drug improves liver function, accelerates the process of removing toxins from the body.

Healing effects:

• Hepatoprotective - liver cells are restored, organ regeneration is accelerated.
• Detoxification - stimulates the work of liver cells.
• Cholagogue - increases the motility of the gallbladder, accelerates the outflow of bile.

Thanks to the combined composition, Dipana has additional properties. Tablets reduce swelling, reduce the permeability of the vascular walls, improve the immune status, activate the barrier functions of the body.

Take 3 tablets 2 times a day. The duration of the course is from 3 months. You can buy at a pharmacy, the cost of 48 tablets is 750 rubles.

Gepabene

Combined natural remedy. In the composition of the extract of milk thistle and medicinal fumes. Gepabene restores the structure of liver cells, normalizes the outflow of bile in biliary dyskinesia. Sold in capsules. The dose and course are selected individually. The price for 30 capsules is 450 rubles.

Prevention of liver diseases

It is important that the treatment and prevention of liver pathologies be carried out in a timely manner. To protect the organ from the hepatotoxic effect while taking drugs and other drugs, it is necessary to strictly follow the dosages prescribed by the doctor. If you feel worse, symptoms of the liver, immediately consult a doctor to correct the treatment.

You can not self-medicate, since many pills, especially in high dosages, adversely affect the functioning of the gland.

Preventive measures also include proper nutrition, physical activity on a regular basis, moderate alcohol consumption. If there is a history of liver disorders, then alcohol should be completely abandoned.

Content

Doctors call the liver a unique organ, because it is able to self-repair if it has more than 25% of healthy cells, therefore, in the treatment of diseases of the hepatobiliary system, especially with degenerative tissue changes, gastroenterologists assign an important role to hepatoprotectors. Drugs that stimulate the accelerated regeneration of hepatocytes are needed not only for serious problems, but also for a person suffering from overeating. How to choose and use them, and is it worth buying inexpensive drugs?

What are Liver Restoration Medications

Hepatoprotectors are the official medical name for drugs that help vulnerable hepatocytes regenerate and protect them from further destruction. An important advantage of such drugs is their relative safety, since most of them have a natural basis: the main side effects are allergic reactions to active ingredients.

Hepatoprotectors for the liver - classification

Domestic gastroenterologists (there are no drugs for liver restoration in foreign medicine) are arguing about the classification of such drugs: they can be divided by origin, chemical composition, mode of action. The conditional general subdivision looks like this:

• Essential phospholipids - are built into the lipid layer of the cell wall, starting its restoration (Livenziale, Rezalyut, Livolife (lecithin)).
• Bile acids - on ursodeoxycholic acid (UDCA), increase the solubility of bile, reduce the number of dying hepatocytes (Ursosan, Ursofalk, Ursoliv).
• Derivatives of amino acids - are components of proteins, therefore they supplement metabolic processes, help to cope with intoxication (Heptral, Hepa-Merz, Remaxol).
• Hepatoprotectors of animal origin - based on ingredients from the liver of cattle, have antioxidant and detoxifying properties, start the restoration of the parenchyma (Hepatosan, Sirepar, Hepatamin).
• Plant hepatoprotectors - based on extracts of artichoke, immortelle, milk thistle (Silibor, Hofitol, Sibektan), act as natural antioxidants. This also includes dietary supplements that may contain tocopherol, B vitamins, improve digestion (Tykveol, LIV-52, Gepafor), and homeopathic remedies (Galsten, Hepel, Helidonium).

Indications for use

The general focus of all categories of hepatoprotectors - the protection of the hepatobiliary system - does not yet indicate that they have a common list of diseases that they cope with. Indications for use are determined by the composition of the drug, so the choice is made only after the diagnosis is made. Gastroenterologists can advise hepatoprotectors for prophylactic purposes, to prepare for duodenal studies, stabilize the condition in case of a threat of heart attack and stroke, and treat:

• cirrhosis (narcotic, alcoholic, autoimmune, viral origin);
• fatty degeneration;
• biliary dyskinesia;
• digestive disorders, accompanied by belching, epigastric pain, loss of appetite, anorexia;
• hepatitis A.

Viral hepatitis

Medicines for the restoration of hepatocytes do not affect pathogenic microorganisms, therefore, in the treatment of viral diseases, they are prescribed only together with antiviral drugs, while combined agents are selected immediately: phospholipids in tandem with interferon. It is not excluded the appointment of hepatoprotectors to prevent the development of the disease, if antiviral therapy cannot be carried out.

Alcoholic - with risk of cirrhosis

Protection from the toxic effects of ethyl alcohol with drugs that trigger the process of cell repair can only be observed when the main prerequisite for the development of the problem is eliminated. If a person does not give up alcohol, but tries to drink hepatoprotectors, there will be no point in treatment - their protective and restorative functions will not work.

Fatty degeneration

On early stages Hepatosis patients are advised to stick to a diet (especially if obesity or diabetes is present) and take inexpensive plant-based liver repair products to slow down the destruction of its cells and stimulate regenerative processes. Help hepatoprotectors and prolong periods of remission, but they need to add a whole list of therapeutic measures. In the later stages of fatty degeneration, they are ineffective.

Medicinal (toxic)

After long-term treatment with antibiotics, hormonal drugs (especially contraceptives, gonadotropin drugs), non-steroidal (NSAIDs), and other drugs with high hepatotoxicity, a long course of hepatoprotectors makes sense, but only when the therapy is over. Simultaneous intake of hepatocyte-restoring compounds and certain drugs (especially antibiotics) reduces the effectiveness of the latter, affecting their metabolism.

Therapeutic effect of drugs for the treatment of the liver

In addition to recovery, which consists in strengthening damaged structures (mainly cell walls) and stimulating the synthesis of protein compounds and enzymes, drugs from the category of hepatoprotectors have the following effect:

• regulate intracellular metabolism;
• protect against the effects of toxins, free radicals;
• block the inflammatory process;
• stimulate the secretion of bile and improve it chemical composition;
• remove slags;
• prevent the development of pathological processes;
• increase the resistance of hepatocytes to adverse factors.

The therapeutic effect of such drugs is not determined by their cost - even inexpensive hepatoprotectors can be highly effective, but only in complex therapy, implying a diet. During their use, it is important to give up alcohol, stop eating junk food (smoked meats, confectionery), avoid overeating and an abundance of fat in the diet. In the presence of diseases of the gastrointestinal tract, especially the pancreas and gallbladder, it is important to establish their functioning in order to see the result from the use of hepatoprotectors.

Preparations for liver restoration - inexpensive and effective

A wide range of hepatoprotectors, which can be found offline or ordered in online pharmacies in Moscow and St. Petersburg (and other Russian cities), has led to the fact that the patient, choosing a good drug, finds it difficult to make a decision. Does it make sense to overpay or can I buy an inexpensive tool? If we focus solely on the effectiveness of such medicines, clinical studies have confirmed a significant positive result only from the use of:

• sources of bile acids;
• amino acid compounds.

The only problem is their high cost - these are not the cheapest drugs for the liver, and not the safest: they are not prescribed for the prevention of overeating, but help treat serious diseases and should be used with caution. The remaining hepatoprotectors do not have proven effectiveness, therefore, they are prescribed as part of complex therapy. For all the drugs listed below, prices are indicated when buying offline - if you need delivery of the drug, its cost depends on the specific online pharmacy.

Essential phospholipids

For the restoration of the cell wall of hepatocytes, its components are responsible, which can be obtained from the outside - essential highly purified phospholipids. Embedding in the structure of the liver, they improve the state of the lipid layer, stimulating the process of membrane repair, do not allow the connective tissue to replace hepatocytes and have a positive effect on protein-fat metabolism and the chemical composition of bile. Medicines on essential phospholipids are prescribed for:

• intoxication;
• hepatitis of any etiology;
• fatty degeneration.

Absorption of phospholipids occurs in the intestine, metabolism (breakdown to fatty acids) in the liver. Phospholipid drugs are well tolerated, they have no contraindications (children - under the supervision of a doctor), rarely cause diarrhea and fluid retention, some tablets (like Phosphogliv) are prohibited for hypertension, but their effectiveness is in doubt. According to clinical trials, such agents increase the response to α-interferon, but:

• their long-term use with alcoholic and viral lesions can provoke stagnation of bile and an increase in the inflammatory process;
• a combination with some vitamins (as in the preparations Gepagard, Rezalut, Essliver Forte) can harm the body.

They are available in the form of gelatin capsules, which are taken before or with meals. Some drugs can be found in ampoules (solutions for parenteral administration) - this is a more effective form that does not provoke adverse reactions from the gastrointestinal tract. The most effective hepatoprotectors based on phospholipids can be seen in the table:

	Compound	Mechanism of action	Indications	Mode of application
Essentiale N	phospholipids from soybeans	restoration of the structure of the organ, support for detoxification functions	the initial stage of cirrhosis; fatty hepatosis; toxic/alcoholic hepatitis	4-6 capsules 2 r / day, course of treatment - 3-6 months
Phosfonciale	silymarin, lipoid C100	inhibits the reproduction of viruses, helps to restore the functioning of hepatocytes	hepatitis; radiation sickness; intoxication; fatty degeneration	2 tablets 3 r / day, with food; course of treatment - 3-12 months
Phosphogliv	phospholipids, sodium glycyrrhizinate	antiviral, immunomodulatory, stimulation of the synthesis of natural lymphocytes	hepatitis; hepatosis; toxic lesions; neurodermatitis, eczema (adjuvant)	2 capsules 3 r / day, course of treatment - 3-6 months
	triglycerides, phospholipids, soybean oil, alpha-tocopherol	stabilization of cell membranes, stimulation of hepatocyte regeneration	hypercholesterolemia; hepatitis; fatty degeneration	2 capsules 3 r / day before meals with water

Herbal preparations

The main herbs that make up the composition of medicines for liver restoration are artichoke, fumes, milk thistle, celandine. They are produced in the form of tablets, syrups, dry raw materials (powder), as most herbal remedies are safe, among the contraindications are mainly individual intolerance and simultaneous use with Diazepam, Ketoconazole, coumarin anticoagulants, fexofenadine. Key features:

• Milk thistle is known as an antidote to the toadstool alkaloid, a powerful antioxidant containing silymarin - a substance that stimulates the growth of new cells, blocks the production of acetaldehyde, prevents the loss of transaminases, and suppresses collagen synthesis.
• Artichoke contains cymarin, has a hepatoprotective property, choleretic, diuretic, affects cholesterol levels, reduces blood azotemia through increased urea excretion.

Clinical efficacy in acute hepatitis of both substances has not been proven (the artichoke is contraindicated in this situation). Silymarin reduces the activity of aminotransferases in patients with chronic disease and it continues to be studied by specialists, and regarding cymarin, it has been found that it helps with toxic forms, but is dangerous for obstruction of the bile ducts by stones and cholestasis syndrome. The main inexpensive medicines on these substances:

		Mechanism of action	Indications	Mode of application
Preparations with milk thistle
	silymarin	improves cellular metabolism, has an antitoxic effect	cirrhosis; inflammatory processes	adults 1-2 tablets 3 r / day, washed down with warm water; the children's dose is considered individually - 3 mg / kg
Silimar	milk thistle fruit extract, lactose		toxic / alcoholic liver damage; cirrhosis; inflammatory processes	2 tablets 3 r / day half an hour before meals
Milk thistle extract	silymarin, silybinin	antitoxic, hepatoprotective, stabilizes the membrane of hepatocytes	toxic / alcoholic liver damage; cirrhosis; inflammatory processes	1 capsule 1 r/day with food
Milk thistle meal	crushed milk thistle fruit	antitoxic, hepatoprotective, stabilizes the membrane of hepatocytes	toxic / alcoholic liver damage; cirrhosis; inflammatory processes	1 tsp powder with food 3 r / day, drink warm water
Preparations based on artichoke extract
	artichoke leaf extract	diuretic, choleretic, influence on microcirculation of blood flow in vessels	cholecystitis; dyskinesia; kidney pathology; atherosclerosis; pregnancy toxemia, preeclampsia	2-3 tablets or 2.5 ml of solution before meals 3 r / day	syrup - 400 rubles, tablets - 300-700 rubles.
	artichoke leaf extract	choleretic, cholesterol lowering	chronic hepatitis; steatosis; chronic colitis; pancreatitis; cholecystitis	1 capsule 2 r / day with food and plenty of liquid	no data
Artichoke extract	artichoke leaf extract	diuretic, choleretic	chronic hepatitis; steatosis; chronic colitis; pancreatitis; cholecystitis	tablets - 3 pcs. 3 r / day; solution - 1 tsp. 3 r / day; ampoules - 100 ml daily with a dropper

Medicines of animal origin

Preparations made from the liver of animals, containing low-molecular metabolites, amino acids, cyanocobalamin, enhance immune responses, therefore, they often provoke allergies. The effectiveness of hepatoprotectors of animal origin has not been clinically proven, doctors even put forward several arguments against them:

• increasing the likelihood of cell decay;
• the risk of infection from animals with infections that provoke neurodegenerative diseases;
• the likelihood of developing an immunopathological syndrome.

Inexpensive, animal-based liver repair drugs come in capsules that dissolve in the gut. Metabolites are excreted by the kidneys. Even with strict adherence to the instructions, adverse reactions are observed: diarrhea, increased salivation, nausea, stool disorders. They are assigned only therapeutic purpose- not for prevention. The most famous inexpensive products from this category:

		Mechanism of action	Indications	Mode of application
	bovine liver hydrolyzate	lipotropic, regenerative, detoxifying	chronic and subacute hepatitis; cirrhosis; drug and toxic effects	intravenously, 2-3 ml at a time; course dose - up to 200 ml	no data
Hepatosan	porcine liver cells	detoxifying, hepatoprotective, adsorbing	cirrhosis; hepatosis; poisoning; digestive disorders	200-400 mg per day, treatment lasts 10-20 days
Hepatamine	proteins and nucleoproteins from livestock liver	inhibits the process of replacing hepatocytes with fibrous tissue, has a detoxifying effect	congestion in the bile ducts; long-term drug therapy; hepatitis; alcohol intoxication; liver failure	1-2 tablets half an hour before meals 3 r / day, course of treatment - 2 weeks

homeopathic remedies

Inexpensive herbal medicines are also present in homeopathy, only their effectiveness has not been proven - most doctors tend to the placebo effect. Such medicines are not subject to clinical trials. The advantages include their relative safety, since they are based on herbal extracts that help cleanse hepatocytes and have a symptomatic effect. The result appears with the accumulation of active substances in the body, so they are prescribed mainly for the treatment of chronic diseases:

• pancreatitis;
• cholecystitis;
• biliary dyskinesia.

Inexpensive homeopathic preparations for the treatment of the liver are produced in the form of tablets, which are washed down with plenty of water, or granules applied sublingually. They are prohibited in acute intoxications, in children they are used only under the supervision of a doctor, and the course of homeopathic treatment can last up to a year. Inexpensive effective medicines of this type:

	Compound	Mechanism of action	Indications	Mode of application	Price
	extracts of celandine, club moss, cinchona, nutmeg, milk thistle, colocynth	antispasmodic, anti-inflammatory, choleretic	complex therapy of dysfunctions of the hepatobiliary system with inflammation	1 tablet 3 r / day, dissolve under the tongue
Galstena	extracts of milk thistle, dandelion, celandine, sodium sulfate, phosphorus	regulates the consistency of bile, relieves spasms and pain in the right hypochondrium	drug and alcohol intoxication; hepatitis	half an hour before meals 1 tablet or 10 drops per 50 ml of water 3 r / day
Chelidonium majus (Chelidonium)	celandine extract	antispasmodic, antitumor, choleretic	pain in the right hypochondrium; chronic hepatitis	10 drops per 30 ml of water half an hour before meals 3 r / day

dietary supplements

Dietary supplements also have controversial effectiveness, according to the comments of doctors - they also belong to herbal medicines, in the composition in the first places are plant extracts: pumpkin seeds, oats, hyssop, ginger, etc. From the plant hepatoprotectors described above, they are distinguished by a combined composition, due to which they often cause a lot of adverse reactions from the digestive system and can cause allergies. Their effect on the body is more preventive than therapeutic:

• improvement of the outflow of bile;
• decrease in the severity of dyspeptic phenomena;
• stimulation of the digestive process;
• start of recovery of hepatocytes;
• protection from toxic effects.

Doctors do not advise using even inexpensive dietary supplements without a prescription from a gastroenterologist, do not prescribe them during pregnancy and lactation, hypersensitivity, inflammatory bowel diseases, and children under 5-12 years old. Such drugs can be produced in capsules and tablets, or in the form of suspensions:

		Mechanism of action	Indications	Mode of application
	extracts of chicory, nightshade, capers, yarrow, tamarisk, emblica	improvement of bile outflow, stimulation of regenerative processes, anti-inflammatory and antitoxic effect	prevention of alcohol damage; radiation and chemical protection	1-3 tablets at a frequency of 2 r / day with food
	extracts of turmeric, oats, volodushka, mint, immortelle	anti-inflammatory action, reparative, antispasmodic, antitoxic	violations of the process of biliary excretion; diseases of the hepatobiliary system	1 tablet 2 r / day with food
Hepato transit	extract of agrimony, corn stigmas, oats, volodushki, lemon juice	choleretic, anti-inflammatory effect, reducing the viscosity of bile	cleansing of the hepatobiliary system; biliary dyskinesia	1 tsp solution per 250 ml of water, 4 r / day
	extracts of andrographis, hyssop, ginger, phyllanthus, eclipta, pyrorchiza, nightshade, tinospora, pepper	normalization of protein-synthetic function, improvement of digestion, stimulation of cell regeneration	prevention and treatment of alcohol abuse; cirrhosis; hepatitis of any etiology; fatty degeneration	2-3 tablets 3 r / day before meals with plenty of water; course of treatment - 4-12 weeks
	pumpkin seed oil (beta-carotene, polyunsaturated fatty acids high in linoleic, oleic)	anti-inflammatory, hepatoprotective, antioxidant	cholestasis; gastritis; cirrhosis; dyskinesia; hepatitis; fatty degeneration; atherosclerosis	4 capsules 3 r / day or 1 tsp. 3 r / day for 30 min. before meals

Bile acids

Inexpensive drugs for liver restoration in this category are few, but the effectiveness covers the high cost. Such drugs work on ursodeoxycholic acid (UDCA), which is obtained from the bile of the Himalayan bear: it is non-toxic and helps to thin the bile of a person, stimulates its excretion. To her positive qualities also include an immunomodulatory property (affects the level of T-lymphocytes), the ability to reduce the "mortality" of hepatocytes. Indications for the use of such drugs are cholestasis caused by:

• stones in the gallbladder (with the exception of cases of their calcification);
• fatty hepatosis;
• prolonged alcohol intoxication;
• primary biliary cirrhosis;
• hepatopathy against the background of pregnancy, oncology, hemophilia.

UDCA is absorbed from the jejunum, binds to plasma proteins, and crosses the BBB. The disadvantage of drugs on bile acids is a large number of contraindications: they are not prescribed for liver failure, stomach ulcers, pancreatitis, inflammatory processes in the gallbladder. Adverse reactions are dyspepsia, diarrhea. These drugs are produced in the form of tablets (capsules) and suspensions:

	Compound	Mechanism of action	Indications	Mode of application	Price
Ursofalk	UDCA, xylitol is present in the suspension	(reducing cholesterol levels)	gall cholesterol stones stones; biliary dyskinesia; cirrhosis; chronic hepatitis	the dosage is considered individually, 10-15 mg / kg, intake 1-3 r / day, the course of treatment is 6-12 months.
		dissolution of gallstones, lipid-lowering effect	biliary reflux gastritis; primary biliary cirrhosis; alcoholic disease; chronic hepatitis; cystic fibrosis	Drink with or after meals
			biliary reflux gastritis; primary biliary cirrhosis; small and medium cholesterol stones; alcoholic disease; chronic hepatitis; cystic fibrosis	the dosage is considered at 10 mg / kg and divided into 3 doses
		dissolution of gallstones, lipid-lowering effect	biliary reflux gastritis; primary biliary cirrhosis; small and medium cholesterol stones; alcoholic disease; chronic hepatitis; cystic fibrosis	the dosage is considered at 10 mg / kg and divided into 3 doses
Livodex	UDCA, lactose present	dissolution of gallstones, lipid-lowering effect	biliary reflux gastritis; primary biliary cirrhosis; small and medium cholesterol stones	the dosage is considered at 10 mg / kg and divided into 3 doses	no price data

Amino acid derivatives

The only group of drugs for the restoration of hepatocytes with a fully proven high degree of effectiveness are derivatives of amino acids. They cannot be called inexpensive, but they were recognized even in European countries, since they have a pronounced hepatoprotective effect, but for maximum effectiveness, use should not be oral, but intravenous. Active components work and are applied as follows:

• Ademetionine - has regenerative, neuroprotective and detoxifying properties, removes fats, stimulates the synthesis of phosphatidylcholine. It is prescribed for alcohol and drug intoxications, primary biliary cirrhosis, chronic viral diseases of the organ.
• Ornithine - reduces the level of ammonia in the blood, is used to treat encephalopathy, non-alcoholic steatohepatitis.

The disadvantage of drugs based on amino acids is a long list of possible side effects: urticaria, anaphylactic shock, angioedema, phlebitis, heart pain, myalgia, persistent asthenia, bloating, pain in the epigastric region, inflammatory skin infiltration, arthralgia. The main characteristics of known drugs:

	Compound	Mechanism of action	Indications	Mode of application	Price
Heptral	adementionine		withdrawal syndrome; toxic hepatitis; fatty degeneration; precirrhotic conditions;	intravenously daily 400-800 mg; orally - 2-4 tablets
	adementionine	choleritic, cholekinetic, antifibrosing, neuroprotective effects	withdrawal syndrome; toxic hepatitis; fatty degeneration; precirrhotic conditions; depression in the elimination of alcohol dependence	tablets - 2-4 pieces / day, without chewing; ampoules - intravenously, up to 800 mg / day
Hepa-Merz		lowering the level of ammonia, stimulating the production of insulin and somatotropic hormone	hepatic encephalopathy; protein deficiency; acute and chronic diseases with hyperammonia	intravenously up to 40 ml / day, with hepatic encephalopathy - up to 80 ml / day

The best drugs

The most effective drug will be the one that is selected to solve a specific problem, so it is impossible to randomly name the best drug. Persons with diabetes are prescribed inexpensive lipoic acid, which is not a pure hepatoprotector, and with cirrhosis and hepatitis, expensive sources of ursodeoxycholic acid cannot be dispensed with. For cleansing, be sure to use formulations in which oats and milk thistle are present.

With cirrhosis of the liver and hepatitis

The maximum efficiency in severe diseases of the hepatobiliary system is shown by drugs produced in the form of solutions for injection. For ease of dosing, they are sold in ampoules, each of which is designed for 1 procedure. The advantage of such funds is the minimum number of contraindications (mainly individual intolerance, pregnancy, childhood). Among the relatively inexpensive drugs for liver restoration in ampoules for outpatient therapy are mentioned:

• Remaxol.
• Essentiale N.
• Criomelt MN.

Accurate recommendations can be given only after clarifying the nature and stage of the disease: in the inactive form, phospholipids are used, in decompensated cirrhosis, lipoic acid (Berlition, Thiogamma) is required, and in cryptogenic, amino acid derivatives are required. If you are considering inexpensive herbal medicines, then pay attention to those where milk thistle extract is present.

Cleansing after medication

Without a doctor's prescription, you can start taking preparations based on milk thistle, dandelion, artichoke and other medicinal herbs(LIV-52, Ovesol, Gepabene) are inexpensive hepatoprotectors with a good effect and a minimum of adverse reactions. Stronger from the position of cleansing the hepatobiliary system are such adsorbents:

• Essliver Forte;
• HeptraLight;
• Allohol.

Organ Maintenance Pills

Prevention of further destruction of hepatocytes in the complex therapy of chronic diseases is provided by herbal preparations (monocomponent sources of milk thistle or artichoke extracts are the most inexpensive), among which dietary supplements are mentioned - like LIV-52, Ovesol. Gastroenterologists can also appoint:

• essential phospholipids (Phosphoglyph, Essliver).
• sources of ursodeoxycholic acid (Ursosan, Ursolfak).

After alcohol

Doctors call medicines based on milk thistle the safest pharmaceutical preparations for restoring the body after alcohol intoxication - they are inexpensive, do not cause side effects, and are used as a food supplement (Karsil, Silimar). Appointment not excluded:

• cleansing compounds - Gepabene, Heptral.
• means for activation of regeneration on amino acids - Dipana, Hepato-transit.

Which pills to choose for children

Most of the drugs that stimulate the restoration of liver cells are used in children only under the supervision of a gastroenterologist or are completely prohibited until the age of 12. With jaundice in newborns, only Galsten and Hepel are allowed to use - this is homeopathy, which gives the least number of adverse reactions. In children older than 3 years, phospholipids are restored according to the Essentiale type. Other means, especially of animal origin, derivatives of amino acids and bile acids are selected only with a doctor.