Instructions for use for Wobenzym tablets. Wobenzym is a systemic enzyme therapy drug. Instructions for use and dosing regimen

Wobenzym instructions for use describe how a deeply thought-out combination of proteolytics (enzymes whose purpose is to break down proteins). This is a set of highly effective enzymes of natural origin with bright pharmacological properties that allow the drug to be used in many areas of medicine: in angiology and rheumatology, surgical practice and gastroenterology, derma-, cardio-neurology, pediatrics and oncology, otolaryngology and dermatology, ophthalmology and gynecology.

Wobenzym instruction presents as a drug of multidirectional action, affecting different structures of the body and the main biochemical processes in them. Wobenzym is a systemic drug whose action consists of antiplatelet, fibrinolytic, decongestant and secondary analgesic effects.

This means that the components of the drug do not allow platelets to stick together, reduce the level of thromboxane in the blood, break down the leading thrombogenic compound - fibrin, improving blood rheology. Along the way, eliminating or reducing signs of inflammation, including pain.

Patients wonder why various diseases additional medicines are needed, for example, what is Wobenzym for? The drug has a positive effect on nonspecific immunity and limits autoimmune reactions of a pathological nature. Enzymes of the drug in the complex have a stimulating effect on antitumor immunity. The drug reduces the content of immune complexes in the blood and their release from tissues.

Wobenzym - instructions for use

The advantage of drugs is the ability of its enzymes to circulate freely in the blood, penetrating into various organs and tissues. human body. This means that after drinking a pill, the patient can be sure that toxic metabolites and decaying tissues will be lysed at any localization of the pathological focus. Here is Wobenzym for which it is prescribed for a variety of diseases and after surgical interventions.

Wobenzym tablets have interesting feature, they organically combine enzymes of animal origin and phyto-ingredients.

The components of the remedy combinatively complement and potentiate the action of each other. Partially binding to antiproteases, specific blood proteins that perform a transport function activate them and acquire the ability to influence the level of:

1. Hormones.
2. Substances responsible for intercellular interaction (cytokines).
3. And β-growth factors, substances involved in the restoration of damaged tissues by the growth of connective tissue.

Due to this, enzymes modify the inflammatory response into an anti-inflammatory one. The cascade inflammatory reaction is interrupted, the process does not become chronic. In addition, the drug acts as an indirect stimulator of scarring of deep lesions of organs and tissues.

Wobenzym has an anti-inflammatory effect

Antiproteases neutralize the antigenic properties of proteases, allowing them to move with the blood stream without “allergy” provocations and fight inflammation. At the same time, part of the enzymes remains in the intestinal lumen, participating in the act of digestion and restoring the balance of microflora in the digestive system. But the lion's share of immunity is beneficial intestinal microorganisms.

Reception described medicinal product neutralizes the negative impact of other aggressive medications of hormonal drugs and antibacterial drugs.

The composition of the drug, working in the human body, affects the cholesterol content, reducing the "bad" in favor of the "useful". Let's not cheat if we attribute the remedy to antioxidants, because its components prevent fat peroxidation.

The drug proved to be excellent in the treatment of various pathologies, obstetricians and gynecologists note its special role. The drug in the true sense of the word can be attributed to the means of a wide therapeutic effect. Despite its active participation in many body processes, Wobenzym does not belong to doping drugs.

Release forms

The described medicine is a combined tablet enzyme of complex action. Another form, except for tablets, is not provided for this medicine.

Once in the patient's body, the tablet, without damage from the acidic contents of the stomach for its components, both plant and animal, is sent to the intestines. The enteric coating protects the active components of the agent from damage, only in the intestines does it melt, releasing useful substances that are actively absorbed through the intestinal wall in the form of intact molecules. And then with the blood flow they enter the inflammatory focus and accumulate there.

The active components of the drug are absorbed by the body through the walls of the intestine

The active components of the drug Wobenzym tablets are:

• bromelain and papaya;
• trypsin and chymotrepsin;
• pancreatin and lipase;
• rutoside and amylase.

Lactose, starch and silicon dioxide are additional ingredients designed to give the rich formulation a compact pill shape.

Contraindications and side effects

Given the rather high price for Wobenzym, the instruction, or rather, that part of it where contraindications are described, is of great interest to patients. Wobenzin is good because with a wide range of pharmacological activity, it has very few contraindications. Unlike many medicines, Wobenzym instructions for use in gynecology do not prohibit treatment for pregnant and lactating women.

You should not take it:

1. With allergies / intolerance to the components of the drug.
2. Patients under the age of 5 years.
3. During hemodialysis (extrarenal blood purification).
4. With pathologies accompanied by bleeding (hemophilia, lack of platelet mass).

The drug is well tolerated due to its natural composition. There have been no cases of drug withdrawal syndrome, addiction to it, even if it is taken in high doses and for a long time. As a possible side reaction, the abstract calls rashes like urticaria.

The use of an enzymatic agent may lead to a slight change in the odor of the stool and the consistency of the feces. More often this happens when taking large doses of the drug. reducing the dosage corrects the situation.

Does not describe critical and even any noticeable shortcomings on Wobenzym instructions for use, the price is the main, and sometimes its only minus. However, if you have negative manifestations that are not described in the annotation, immediately go to the doctor, stopping taking the remedy until the situation is clarified.

The instructions for use are very impressive for the Wobenzym remedy, the reviews on the remedy are positive from many categories of patients, we will consider in which cases doctors consider it necessary to prescribe this medicine.

For honey. the drug Wobenzym indications for use are:

1. In surgery and traumatology - postoperative conditions. The medication prevents the development of hematomas and edema or accelerates their resorption.
2. In angiology, these are vascular lesions: phlebitis, thrombosis, combined pathology (thrombophlebitis), endarteritis, atherosclerosis of the vessels of the legs.
3. In urology and gynecology - prostatitis and chronic lesions of the genitals, STDs and adnexitis, cystitis and cystopyelitis, hormone replacement therapy, preeclampsia and mastopathy.
4. In dermatology - acne and atopic dermatitis.
5. In cardiology: angina pectoris, with coronary artery disease to improve blood rheology.
6. In gastroenterology - pancreatitis and hepatitis.
7. In pulmonology - inflammation of the lungs and bronchitis, sinusitis.
8. In endocrinology and ophthalmology: angiopathy and retinopathy, hemophthalmia and iridocyclitis, uveitis associated with diabetes, autoimmune thyroiditis, eye microsurgery.
9. In nephrology, inflammation of the kidneys.
10. In neurology - multiple sclerosis.
11. In rheumatological practice - inflammation of the joints (arthritis), ankylosing spondylitis.
12. In pediatrics - juvenile arthritis of rheumatoid nature, atopic dermatitis, diseases of the respiratory system, postoperative conditions and complications.

Despite the fact that the price of Wobenzym is very high, the instructions for use recommend this enzymatic preparation as a prophylactic. And in this capacity, the composition is also actively used to prevent the development of adhesions and infection after surgery, side effects treatment with hormones, after suffering stress and violations of adaptation mechanisms.

We will also use the medication as a “cover” drug for chemotherapy and oncology treatment with radiation methods.

Studying the instructions for use, reviews, price on Wobenzym, one cannot help but dwell on the rules for taking the medicine. It is taken in courses from 2 weeks in case of acute pathology to 3-6 months in case of chronic process.

The daily dose of the drug for adults is from 9 to 30 tablets, divided into 3 doses. Children aged 6-12 years should receive medicine based on body weight. For every 6 kg, you need to give 1 tablet per day. The medicine is drunk without chewing and with a glass of water.

The cost of the drug

On Wobenzym the price is quite high. It is sometimes difficult to navigate by looking on the Internet, because the indicated price “run-up” is thousands of rubles (from 178 to 6100 rubles per pack).

Let's take a closer look at the intricacies of the cost of the drug: 17890-1820 rubles for the drug Wobenzym, the price of 200 tablets, the price of 800 pills will already be about 5500-6080 rubles. In the first case, the medicine is offered by Iatrium Innovation Rus (Germany), in the second case, by Mukos Emulsions GmbH (Germany), 20 tablets of drugs cost 178-1200 rubles. But given the daily dose and therapeutic course, it hardly makes sense to purchase the drug in the amount of 20-40 tablets.

Similar drugs

Given the cost of the drug, it is not surprising that patients are looking for cheap analogues for Wobenzym drugs. Unfortunately, the pharmaceutical market does not offer direct structural analogues of drugs, especially cheaper ones. As Wobenzym analogues, various enzymatic drugs and dietary supplements are presented. For example, the herbal-enzymatic drug Evenzym, close to the drug Wobenzym, is considered as an analogue of Wobenzym. Other enzymatic agents are also called Wobenzym's analogue:

• Ronidaza,
• Longidaza.

In this capacity, Aesculus, Cytochrome-C and other agents are considered.

Considering the large number of possibilities of the drug and its considerable price, having studied the instructions for use, price, and reviews on the drug Wobenzym, any patient will probably be interested. Let's consider some of them.

Summary of Reviews

Interestingly, among physicians, reviews on Wobenzym are contradictory, although doctors willingly prescribe it. In the homeland of the drug, it is classified as a dietary supplement of a sports profile. Some doctors consider the effectiveness of the drug with a placebo effect, others believe that it is quite effective. Wobenzym is sometimes described by doctors as a diet replacement pill.

What used to be treated by harmonizing the diet is now eliminated by enzymatic means. Nevertheless, as indicated on the drug Wobenzym by the instructions for use in gynecology, patient reviews confirmed its significant beneficial effect on the body. The tool is actively used to treat pregnant and lactating women.

However, you should not place crazy hopes on the medicine. Wobenzym in gynecology reviews describe how a medicine that does not help everyone solve problems with infertility in endometriosis and synechia.

Patients are also contradictory in their reviews. For some, it has become a lifesaver. Although the effect of it is not instantaneous and improvement comes slowly towards the end of the course. Others consider the remedy useless, and dangerous in large doses, because they experienced nausea, dizziness and other unpleasant sensations when taking it. The question of the correctness of taking the medication remains open, as well as the need for additional fermentation. The remedy helped many patients and the main complaint from them is the cost of the remedy. It is considered unreasonably high by both doctors and patients.

Wobenzym: instructions for use, price, reviews, analogues are presented for a more detailed acquaintance with the drug. But relying on the article as a reason to take medicine or refuse treatment is not worth it.

Content

Alternative medicines of systemic enzyme therapy are gaining popularity today. They prevent complications from infectious diseases, help restore the microflora during antibiotic treatment, enzymes reduce inflammation, support the body during hormone therapy. Find out why Wobenzym is prescribed medicine - instructions for use, indications for treatment, the effect of tablets on the body.

What are Wobenzym tablets

This is a combined drug developed on the basis of highly active enzymes of plant and animal origin. The drug is produced exclusively in the form of tablets coated with a thin enteric coating. The drug has a slight vanilla smell. Inside the package with Wobenzym tablets are instructions for use and blisters of 2 or 10 pieces, complete with 20 tablets. Sometimes the product can be bought in durable plastic bottles.

Why are they prescribed

For prophylactic purposes, the drug is used for disorders of blood microcirculation, to eliminate side effects from hormone replacement therapy, to treat dysbiotic disorders from the use of antibiotics. Wobenzym is effective for colds, during periods of acclimatization and in post-stress situations. The scope of the drug in pediatrics is the treatment of atopic dermatitis in a child, infectious viral diseases of the upper respiratory tract and children's arthritis.

Ingredients of Wobenzym

This medication has a positive effect on the digestive tract, relieves inflammation, and prevents the development of complications. All these properties are possessed by natural enzymes, successfully combined in one tablet. The dragee contains 250 mg of active ingredients derived from plants or animal pancreas, plus excipients.

active ingredients

During oral administration of Wobenzym, the active components are rapidly absorbed from the intestinal walls with the formation of a protein enzyme, which enters all vital organs with the blood stream. The amount of these ingredients varies, and in official instructions most of them are presented in units of the European Pharmacopoeia, and only pancreatin is described according to the standards of the International Pharmaceutical Federation. One tablet contains:

• rutose - 50 mg;
• pancreatin - 345 units;
• papain - 90 units;
• amylase - 50 units;
• bromelain - 225 units;
• trypsin - 360 units;
• lipase - 34 units;
• chymotrypsin - 300 units.

Excipients and shell composition

The action of the active components is enhanced with the help of excipients. They affect the rate of release and absorption of the drug. The quantitative content of auxiliary components, from a medical point of view, is not so significant. The additional composition of Wobenzym includes:

• stearic acid;
• lactose;
• corn starch;
• magnesium stearate;
• talc;
• purified water;
• colloidal silicon dioxide.

Externally, the tablets are covered with a thin, easily soluble shell. Its smooth surface is painted in red-orange color. There should be no additional markings or marks on the surface of the original dragee. The composition of the shell consists of:

• povidone;
• crimson and yellow-orange dye;
• talc;
• vanillin;
• white clay;
• sucrose;
• shellac;
• methyl methacrylate and methacrylic acid;
• titanium dioxide;
• wax;
• macrogol 600;
• triethyl citrate.

How the drug works

All the enzymes included in the composition are selected in such a way that the drug can provide the widest possible spectrum of clinical action. Positive properties Wobenzyma are manifested as follows:

• The drug has an anti-inflammatory, antimicrobial, immunomodulatory effect, increases the fibrinolytic activity of the blood, regulates metabolic mechanisms, improves tissue permeability and saturates them with oxygen.
• Wobenzym increases the release of protein detritus (decay product) from the inflamed area and accelerates the destruction of toxins, corrects the number of lymphocytes, reduces the concentration of thromboxane and other thyroid antibodies.
• Under the influence of Wobenzym, hematomas dissolve faster, dying tissue structures are removed from the body, and swelling decreases.
• Enzyme combinations reduce the severity of side effects and hypercoagulability (increased blood clotting) on ​​hormone therapy, increase the effectiveness of antibiotics.
• Regular use of the drug helps to reduce the level of bad cholesterol, increases the plasticity of red blood cells, normalizes platelet counts, regulates the viscosity of blood plasma, and normalizes the permeability of the walls of blood vessels.
• Enzymes have a beneficial effect on the digestive tract, normalize lipid metabolism, improve the absorption of polyunsaturated fatty acids.

Indications for use

The manufacturer positions the medication as an additional remedy for prevention or in complex treatment with other medications of certain diseases of the internal organs. The main Wobenzym user guide is an instruction for use, which states the advisability of using the product in the following areas of medicine:

1. Gynecology and urology:
   • preeclampsia;
   • mastopathy;
   • chlamydia;
   • cystitis;
   • prostatitis;
   • mycoplasmosis;
   • endometritis;
   • cervicitis;
   • ureaplasmosis;
   • the threat of abortion (2-3 trimester);
   • salpingoophoritis.

1. Cardiology:
   • subacute stage of myocardial infarction;
   • angina.
2. Gastroenterology:
   • dysbiosis of the gastric mucosa;
   • hepatitis;
   • chronic inflammatory processes in different parts of the gastrointestinal tract.
3. Drug in endocrinology:
   • retinopathy;
   • diabetic angiopathy;
   • autoimmune thyroiditis.
4. Angiology:
   • thrombophlebitis;
   • prevention of recurrent phlebitis;
   • post-thrombophlebitic disease;
   • atherosclerosis of the legs;
   • endarteritis.
5. Otolaryngology and pulmonology:
   • bronchitis;
   • otitis;
   • tuberculosis;
   • sinusitis;
   • sinusitis;
   • pneumonia;
   • laryngitis;
   • obstructive bronchitis.
6. Application in ophthalmology:
   • glaucoma;
   • hemophthalmos;
   • uveitis.
7. Children in pediatrics:
   • acute respiratory viral diseases of the upper respiratory tract;
   • atopic dermatitis;
   • adhesive disease;
   • local swelling or suppuration of soft tissues.
8. Other indications:
   • osteoarthritis;
   • rheumatoid arthritis;
   • illnesses oral cavity infectious nature;
   • pyelonephritis;
   • inflammation of soft tissues after surgery;
   • multiple sclerosis;
   • chronic cerebrovascular accident;
   • acne;
   • dermatoses.

Medicine Wobenzym - instructions for use

Taking the drug does not appear in doping control tests and does not affect driving or operating complex mechanisms in any way. Tablets do not cause drowsiness, but at the beginning of the course of treatment they can exacerbate the symptoms of the disease. If such cases occur, it is necessary to take the medication in a reduced dosage for some time, but not to interrupt the treatment.

For moderate pain conditions

The duration of treatment for moderate conditions is 14 days, during which the patient is recommended to take Wobenzym at a dose of 15 to 21 tablets per day. For convenience, the indicated volumes must be divided into several steps. After the main course of therapy has been completed, a single dosage for the next two weeks is reduced to 3-5 tablets - the daily volume is 9-15 tablets.

In severe form of the disease

In complex pathological conditions, the drug is taken for 2-3 weeks up to 10 tablets at a time three times a day. Then the dosage is gradually reduced to 15 tablets per day, which are divided into three doses. In this rhythm, treatment is continued for 2-3 months. Wobenzym does not replace antibiotics that a doctor will prescribe for a severe form of the disease, but may increase their effectiveness.

For chronic pathologies

Chronic inflammation and other protracted diseases in adults are treated with long courses of 3-6 months. The doctor selects the optimal dosage of Wobenzym for each patient. For children with recurrent inflammatory diseases, a course of 2-3 weeks and taking 2 tablets 2 times a day is recommended. To achieve a stable remission, the duration of treatment can be changed at the discretion of the doctor.

Wobenzym to improve the effectiveness of antibiotics

The drug is often recommended for co-administration with antibiotics. The active components of the agent enhance the effectiveness of antibiotic therapy and serve as a prophylaxis for intestinal dysbacteriosis. Throughout the course, it is recommended to drink 5 tablets three times a day, and after the end of therapy, continue preventive treatment to restore microflora, but with a decrease in a single dose to 3 tablets.

"Cover therapy" in the treatment of oncology

For the prevention of infectious complications, better tolerance of chemotherapy or radiation therapy, strengthening the general health of the patient, cancer patients are prescribed Wobenzym tablets. During irradiation or when taking chemicals appoint 5 tablets 3 times a day until the end of the course of therapy. Physicians may then prescribe Wobenzym as an immune booster with a 21 day regimen of 9 tabs/day.

How to drink Wobenzym

The dosage and treatment regimen may be changed at the discretion of the doctor, depending on the indications of the test results or the severity of the disease. Wobenzym - instructions for use says that you need to take the tablets without biting, at least half an hour before meals or 2-3 hours after eating. It is desirable to drink the drug with ordinary filtered water in sufficient quantities.

Dosage and administration rules for adults

The first three days after the appointment of the drug, adults are recommended to drink 3 tablets three times a day. Then, based on the results of the tests, the dosage can be adjusted from three to 10 tablets per day. The average course of treatment is 2-3 weeks, but can be extended by another 10 days if early antibiotic treatment is taken into account. The official Wobenzym guide - the instructions for use itself states that the drug can be used during pregnancy and breastfeeding.

Wobenzym for children

In pediatrics, such a medicine is prescribed only for children older than five years of age in order to strengthen immunity or as complex therapy in infectious diseases. Standard doses of the drug may vary depending on the weight of the child and the severity of the symptoms. As a rule, children from 5 to 12 years old are recommended to be treated with 3-5 tablets of Wobenzym three times a day. For a child over 12 years old daily rate taken as for an adult.

How to take Wobenzym for prevention

The medication is recommended by doctors as effective remedy prevention of complications in infectious and viral diseases, a supporting drug during the treatment of chronic diseases and a means to improve the quality of life of cancer patients. With a preventive purpose, to reduce the risk of developing heart disease or when adapting, Wobenzym should be taken in a course of 3-6 weeks, 2-3 tablets three times a day. Treatment should be repeated 2-3 times a year.

Side effects and contraindications

According to the instructions, with hemophilia, thrombocytopenia and people with individual intolerance to one or more components, the drug is prohibited. With caution, it is worth drinking pills for pregnant women from 1 to 14 weeks, provided that other medications are taken. Even in the treatment of chronic long-term illnesses, addiction/withdrawal syndromes or cases of drug overdose have not been noted. Wobenzym is well tolerated by patients, but rarely there may be:

• nausea or vomiting;
• heaviness in the stomach;
• violation of the chair;
• change in the smell of feces, diarrhea;
• allergic reactions - skin rashes, itching, urticaria.

How much does wobenzym cost

A pack of tablets can be purchased through pharmacy chains or ordered at a lower price through an online pharmacy catalog. The drug is dispensed without a doctor's prescription, and its price depends on the region of sale and the form of release of the drug. Where to buy Wobenzym inexpensively in Moscow and St. Petersburg is described in the table:

The effectiveness of Wobenzym - truth or myth

The drug is officially registered in Russia as a drug, the same confirmation was given to Wobenzym in European countries, and only in the USA is it considered a dietary supplement. The original composition of Wobenzym was developed by Professor Wolf and Dr. Benitez in the 50s of the last century. During this time, the drug was used in six clinical studies involving more than 2400 patients.

Due to the positive effect on the human body, many doctors consider Wobenzym an indispensable assistant in radiation therapy and hormone replacement treatment. There are many positive reviews from gynecologists about Wobenzym. They believe that this medication is effective for inflammation of the appendages, colpitis and cystitis. However, the drug should not be considered a universal remedy. Remember that all of it positive traits revealed only with an integrated approach to the problem.

Wobenzym's analogs

Absolutely similar in composition of drugs does not exist, but there are drugs belonging to the same pharmacological group. The most common analogues are: Anaferon, Immunal, Imudol, Ribomunil, Waxom. If compared by composition, then Wobenzym can replace:

• Wobe-mugos E - has the same non-specific properties, plus there is a secondary analgesic effect. The average price is 950 rubles.
• Phlogenzym - additionally improves the viscosity of bronchial secretions, promotes sputum discharge. Its cost is 2900 rubles.

Wobenzym is a drug with anti-inflammatory, immunostimulating, fibrinolytic, decongestant and secondary analgesic effects. Instructions for use prescribes taking tablets in gynecology, urology, cardiology and other fields of medicine. Patient reviews and doctors' recommendations report that this drug helps in the treatment of cystitis, thrombophlebitis and STIs.

Release form and composition

Wobenzym is available in the form of film-coated tablets. orange color with a pronounced specific odor.

Each tablet contains active ingredients:

• Lipase.
• Amylase.
• Rutin.
• Papain.
• Trypsin.
• Chymotrypsin.
• Bromelain.

pharmachologic effect

The drug Wobenzym is a complex of highly active animal and plant enzymes (enzymes). These enzymes are carefully selected, optimally combined and included in Wobenzym tablets, from which they have a fairly wide range of clinical applications.

Taking the medication has a positive effect on the course of the inflammatory process, reduces the pathological symptoms of immunocomplex and autoimmune reactions, and has a positive effect on the immunological reactivity of the human body.

Under the action of the active ingredients of the drug, the number of immune complexes circulating in the blood decreases and their membrane deposits are removed from the tissues. The drug activates and corrects the functionality of natural killers (lymphocytes) and macrophage monocytes, stimulates phagocytic cellular activity, cytotoxic T-lymphocytes and antitumor immunity, for which Wobenzym is often prescribed as an immunomodulator.

The prescription of the drug enhances the effectiveness of ongoing antibiotic therapy by increasing the level of antibacterial agents in the focus of inflammation and their plasma concentrations, starts the process of non-specific defense of the body (production of interferons), thereby exhibiting antimicrobial and antiviral effects, and also eliminates the symptoms of dysbacteriosis.

Also, the drug reduces the severity of side effects that occur when taking hormonal drugs (including hypercoagulability).

What is Wobenzym (tablets) prescribed for?

Indications for the use of the drug include the treatment and prevention of the following conditions:

• In gynecology and obstetrics: inflammatory diseases of the uterus and appendages, frequent miscarriages against the background of beriberi and general weakness of the body, mastopathy, lactostasis, recurrent vaginal candidiasis.
• In cardiology: prevention of myocardial infarction in patients at risk, ischemic disease heart, atherosclerosis, aortic aneurysm.
• In traumatology: numerous fractures, dislocations, sprains, bruises, craniocerebral injuries.
• In urology: inflammatory diseases of the urinary organs - cystitis, urethritis, pyelonephritis, glomerol nephritis, urolithiasis.
• In gastroenterology: acute and chronic diseases of the stomach and duodenum, colitis, pancreatitis, Crohn's disease.
• In neurology: multiple sclerosis, neuroses, complex treatment of vegetovascular dystonia with panic attacks.
• In dermatology: complex treatment of dermatitis of various etiologies, eczema, neurodermatitis, acne, carbuncles, boils.
• In surgery: treatment of adhesions against the background of previous surgical interventions, treatment, prevention postoperative complications(suppuration of wounds, accession of a secondary bacterial infection, inflammation, thrombosis).
• In pulmonology: chronic and acute bronchitis as part of complex therapy, laryngitis, pneumonia, bronchopneumonia, bronchial asthma.
• In rheumatology and angiology: as part of complex therapy for rheumatoid arthritis, ankylosing spondylitis, rheumatism, vasculitis, thrombophlebitis, inflammatory processes of the lymphatic vessels.

Wobenzym tablets are prescribed to patients as part of complex therapy for viral and infectious diseases in order to get well soon and reduce the risk of complications. The drug is also prescribed to patients during the course of chemotherapy or radiation therapy in order to prevent the development of severe side effects.

Under the influence of the drug, the risk of side effects during hormonal therapy, including oral contraceptives, is significantly reduced.

Instructions for use

Wobenzym is prescribed in a dosage that is set individually depending on the severity of the disease. Adults, depending on the activity and severity of the disease, are prescribed at a dose of 3 to 10 tablets 3 times a day. In the first 3 days of taking the drug, the recommended dose is 3 tablets 3 times a day.

With an average activity of the disease, the drug is prescribed at a dose of 5-7 tablets 3 times a day for 2 weeks. In the future, the dose of the drug should be reduced to 3-5 tablets 3 times a day. The course is 2 weeks. With high disease activity, the drug is prescribed at a dose of 7-10 tablets 3 times a day for 2-3 weeks. In the future, the dose should be reduced to 5 tablets 3 times a day. The course is 2-3 months.

In chronic long-term diseases, Wobenzym can be used according to indications in courses of 3 to 6 months or more. In order to increase the effectiveness of antibiotics and prevent dysbacteriosis, Wobenzym should be used throughout the course of antibiotic therapy at a dose of 5 tablets 3 times a day. After stopping the course of antibiotic therapy to restore the intestinal microflora, Wobenzym should be prescribed 3 tablets 3 times a day for 2 weeks.

During radiation and chemotherapy, Wobenzym should be used at a dose of 5 tablets 3 times a day until the completion of the course of radiation and chemotherapy in order to prevent infectious complications, improve the tolerability of basic therapy and improve the quality of life.

For prophylactic purposes, Wobenzym is prescribed 3 tablets 3 times a day for 1.5 months with a course repeated 2-3 times a year.

Children aged 5-12 years are prescribed in a daily dose at the rate of 1 tablet per 6 kg of body weight. For children over 12 years of age, the drug is prescribed according to the scheme intended for adults. The duration of treatment is determined individually. The drug should be taken at least 30 minutes before meals, without chewing, with water (200 ml).

Contraindications

• Hypersensitivity to the components of the drug.
• Diseases associated with an increased likelihood of bleeding (thrombocytopenia, hemophilia).
• Children's age up to 5 years.
• Carrying out hemodialysis.

Side effects

Wobenzym is usually well tolerated, provided that the basic recommendations for its use are observed: the tablets should not be chewed, it is also necessary to observe the intervals between taking the drug and food (30 minutes before or 2 hours after a meal).

In some cases, during therapy, the development of such side effects as: slight changes in the smell and consistency of feces, vomiting, nausea, heaviness in the stomach, diarrhea, skin rashes in the form of urticaria, allergies to the components that make up the drug.

These symptoms disappear when the dose is reduced or the drug is discontinued. The syndrome of addiction and withdrawal was not detected even with prolonged therapy with high doses. With the development of adverse reactions not noted in the instructions, it is recommended to cancel the treatment and consult a doctor.

Children, during pregnancy and lactation

Perhaps the appointment of the drug during pregnancy and lactation. Reception is carried out under strict medical supervision. Contraindicated under the age of 5 years.

special instructions

It should be borne in mind that at the beginning of taking Wobenzym, the symptoms of the disease may worsen. Interrupt treatment in such cases should not be, it is recommended to temporarily reduce the daily dose of the drug.

In infectious diseases, Wobenzym does not replace antibiotics, but increases their effectiveness by increasing their concentration in microbial colonies, tissues and inflammation. The drug is not doping and for driving a car and performing work that requires a high speed of physical and mental reactions, negative impact does not render.

drug interaction

With the combined use of Wobenzym tablets with other drugs belonging to different drug groups, no negative interactions were found.

Wobenzym's analogs

Analogues have a similar effect:

1. Wobe-mugos E.
2. Phlogenzym.
3. Engystol.
4. Galavit.
5. Immunal.
6. Broncho Wax.
7. Imudon.
8. Ribomunil.
9. Neuroferon.

Holiday conditions and price

The average price of Wobenzym (40 tablets) in Moscow is 410 rubles. The drug is dispensed in pharmacies without a doctor's prescription.

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MUCOS PHARMA Mucos Emulsions GmbH

Country of origin

Germany

Product group

Immunomodulatory drugs and immunosuppressants

Anti-inflammatory and immunomodulatory drug

Release forms

• 20 - blisters (10) - packs of cardboard. 20 - blisters (2) - packs of cardboard. 20 - blisters (2) - packs of cardboard. 800 - high density polyethylene vials

Description of the dosage form

• Enteric coated tablets

pharmachologic effect

Combined drug. It is a combination of highly active enzymes of plant and animal origin. It has an immunomodulatory, anti-inflammatory, fibrinolytic, anti-edematous, antiplatelet and secondary analgesic effect. Wobenzym has a positive effect on the course of the inflammatory process, limits the pathological manifestations of autoimmune and immunocomplex processes, and has a positive effect on the parameters of the body's immunological reactivity. Stimulates and regulates the functional activity of monocytes-macrophages, natural killers, stimulates antitumor immunity, cytotoxic T-lymphocytes, phagocytic activity of cells. Under the influence of Wobenzym, the number of circulating immune complexes decreases and the membrane deposits of immune complexes are removed from tissues. Wobenzym reduces the infiltration of the interstitium by plasma cells. It increases the elimination of protein detritus and fibrin deposits in the area of ​​inflammation, accelerates the lysis of toxic metabolic products and dying tissues, improves the resorption of hematomas and edema, and normalizes the permeability of vascular walls. Wobenzym reduces the concentration of thromboxane and platelet aggregation. Regulates the adhesion of blood cells, increases the ability of erythrocytes to change their shape by regulating their plasticity, normalizes the number of normal discocytes (platelets) and reduces the total number of activated forms of platelets, normalizes blood viscosity, reduces the total number of microaggregants, thus improving microcirculation and rheological properties of blood, and also supplying tissues with oxygen and nutrients. Wobenzym normalizes lipid metabolism, reduces the synthesis of endogenous cholesterol, increases the content of HDL, reduces the level of atherogenic lipids, improves the absorption of polyunsaturated fatty acids. Wobenzym increases the effectiveness of antibiotic therapy by increasing the concentration of antibiotics in blood plasma and inflammation, and also reduces the side effects of antibiotics (dysbacteriosis). Wobenzym reduces the severity of side effects associated with taking hormonal drugs (including hypercoagulability). Wobenzym regulates the mechanisms of nonspecific protection (production of interferons), thereby exhibiting antiviral and antimicrobial effects.

Pharmacokinetics

After taking Wobenzym orally, the enzymes that make up the drug are absorbed from the small intestine by resorption of intact molecules and, by binding to blood transport proteins, enter the bloodstream. Then the enzymes, migrating along the vascular bed, accumulate in the area of ​​the pathological process.

Special conditions

It should be borne in mind that at the beginning of treatment with Wobenzym, an exacerbation of the symptoms of the disease is possible. In such cases, it is recommended to temporarily reduce the dose, treatment should not be interrupted. In infectious and inflammatory diseases, Wobenzym does not replace antibiotic treatment, but increases their effectiveness. Wobenzym is not doping. Influence on the ability to drive vehicles and control mechanisms The drug does not adversely affect the ability to drive a car and perform work that requires a high speed of psychomotor reactions.

Compound

• pancreatin 345 prot.U.Ph.Eur. papain 90FIP rutoside 50 mg bromelain 225FIP trypsin 360FIP lipase 34FIP amylase 50FIP chymotrypsin 300FIP Excipients: lactose, corn starch, magnesium stearate, stearic acid, purified water, colloidal silicon dioxide, talc, sucrose. Tablet shell composition: sucrose, talc, copolymer of methacrylic acid and methyl methacrylate, shellac, titanium dioxide, white clay, yellow-orange dye (E110), crimson dye 4R (E124), povidone, macrogol 6000, triethyl citrate, vanillin, bleached wax, wax carnauba.

Wobenzym indications for use

• As part of complex therapy: - thrombophlebitis (including acute thrombophlebitis of superficial veins), postphlebitic syndrome, obliterating endarteritis and atherosclerosis of the arteries of the lower extremities, lymphatic edema, prevention of recurrent phlebitis; - cystitis, cystopyelitis, prostatitis; - sexually transmitted infections; - chronic infections of the genitals, gestosis, mastopathy, adnexitis, to reduce the frequency and severity of side effects of hormone replacement therapy in gynecology; - angina pectoris, subacute stage of myocardial infarction (to improve the rheological properties of blood); - sinusitis, bronchitis, pneumonia; - pancreatitis, hepatitis; - pyelonephritis, glomerulonephritis; - diabetic angiopathy, diabetic retinopathy; - autoimmune thyroiditis; - rheumatoid arthritis, reactive arthritis, ankylosing spondylitis; - atopic dermatitis, acne; - multiple sclerosis; - uveitis, iridocyclitis, hemophthalmia, use in ophthalmic surgery;

Wobenzym contraindications

• - diseases associated with an increased likelihood of bleeding (including hemophilia, thrombocytopenia); - carrying out hemodialysis; - children's age up to 5 years; - individual intolerance to the drug

Wobenzym side effects

• Wobenzym is generally well tolerated by patients. In most cases, side effects, withdrawal syndrome, addiction were not observed even with prolonged use in high doses. In some cases: slight changes in the consistency and smell of feces, urticaria (pass when the dose is reduced or the drug is discontinued). The patient should be warned that if other adverse reactions occur, it is recommended to stop taking the drug and consult a doctor.

drug interaction

With the simultaneous use of Wobenzym with other drugs, cases of incompatibility are unknown.

Overdose

No cases of overdose of Wobenzym have been reported.

Storage conditions

• keep away from children

Information provided

Today, patients are often prescribed rather aggressive drug therapy, which can cause significant harm to health. To eliminate the negative consequences of such treatment, many patients use the German-made drug Wobenzym. With prolonged systemic use, this drug has a lot of positive effects and normalizes many physiological processes in a short time.

It is produced only for oral administration in the form of tablets, so some women do not fully understand the need for its use. To refute all doubts, you need to take a closer look at the drug and understand how it can help with a variety of female diseases.

Reviews of "Wobenzyme" in gynecology will be considered in this article.

Release form and composition of the drug

The drug is produced in the form of rounded convex tablets with a red shell. They are packaged in blisters of 20 pieces and packed in cardboard boxes of 2 or 10 plates, or in plastic bottles of 100 or 800 tablets. The cost of the drug directly depends on the number of tablets in the package.

The medicine in its composition contains animal and plant enzymes, as well as other substances that are very important for the human body:

• bromelain and papain - proteolytic enzymes of plant origin, which are isolated from pineapple and papaya, respectively;
• pancreatin - a natural enzyme agent synthesized by the pancreas;
• amylase - an enzyme of natural origin, which is contained in the secret of the pancreas and saliva;
• chymotrypsin and trypsin - pancreatic enzymes with high activity;
• rutin is an antioxidant, which belongs to the number of flavonoids.

In addition to the main active substances, the drug contains auxiliary components that are designed to maintain the stability of the drug throughout the entire shelf life, as well as to impart external characteristics and resistance of the coating layer to gastric juice. This is confirmed by the instructions.

According to reviews, "Wobenzym" in gynecology is very effective.

Pharmacological properties

When ingested, the drug passes through the stomach and enters the small intestine almost unchanged, in which the layer covering the tablet is absorbed, and the active substances are released and enter the bloodstream, where they:

• due to the improvement of the plasticity of erythrocytes, they increase the supply of oxygen to the cells of the body;
• prevent the formation of blood clots, reducing the ability of platelets to stick together;
• destroy harmful compounds (for example, free radicals).

Some components linger in the intestines and positively affect its functioning. They also improve the digestibility of carbohydrates, proteins, vitamins and other nutrients.

Reviews about Wobenzyme in gynecology are mostly positive. The patients who needed to take it, as well as the doctors themselves, speak well of the drug.

In general, the drug provides:

• anti-inflammatory action;
• analgesic effect;
• immunomodulatory action;
• fibrinolytic effect (resolves blood clots);
• anti-edematous effect.

In addition, acceptance medicinal product in combination with other medicines, including chemotherapy drugs and antibiotics, enhances their therapeutic effect, which is very important for the treatment of sexually transmitted diseases. This allows you to significantly reduce the dosage of harmful drugs and minimize the risk of developing negative consequences of taking them.

Also, the drug restores the activity of liver cells, which entails an increase in the quality of its antitoxic function. This improves the cleaning of the bloodstream from toxins and other harmful compounds.

Very detailed instructions for the drug (according to reviews). The insert gives complete information about the drug, indications and contraindications, dosage and frequency of administration. Patients do not need to ask the doctor additional questions about the drug, all the answers to possible questions are already contained in the instructions.

Pharmacokinetics

Immediately after taking the drug, the enzymes that make up the drug are absorbed from the small intestine by resorption of intact molecules. They bind to transport proteins in the blood, enter the bloodstream. Then the enzymes migrate through the vessels and accumulate in the area of ​​pathology.

"Wobenzym" in gynecology: indications for use

Due to its extensive pharmacological properties and high safety, the agent is widely used in gynecology:

• For the treatment of endometriosis - a disease accompanied by the appearance of mucosal areas prone to monthly exfoliation and bleeding.
• In inflammatory diseases of the appendages, cervix and vagina (vaginosis, adnexitis, cervical erosion, cervicitis, colpitis, vaginitis, salpingoophoritis, oophoritis) to improve tissue healing, eliminate edema, reduce the risk of adhesions.
• As part of the complex treatment of STDs (ureaplasmosis, mycoplasmosis, chlamydia, etc.) to increase the concentration of the antibiotic in the affected focus and reduce its harmful effects on the body. The indications for the use of Wobenzym in gynecology must be strictly observed. Reviews are discussed in more detail below.
• For the treatment of ovarian cysts - a hollow benign neoplasm.
• During abortion or ectopic pregnancy to accelerate the healing process of tissues.
• With the formation of adhesions and keloid scars due to surgical intervention. Adhesions can lead to infertility due to obstruction of the fallopian tubes.

The drug "Wobenzym" is highly effective in preventing the occurrence of adhesions, which negatively affect physiological processes, and sometimes even lead to infertility due to the formation of an obstruction in the fallopian tubes and uterus.

How does he work?

"Wobenzym" in gynecology (according to reviews) helps to eliminate:

• edema;
• pain;
• reduces inflammation time.

All of the above is achieved by strengthening the immune system and improving blood circulation in the lesion.

Also, "Wobenzym" is used in gynecology in case of miscarriage and the threat of termination of pregnancy to improve blood flow to the placenta, as well as to eliminate toxicosis, swelling and improve the adaptation of the female body to hormonal changes.

The drug is often prescribed to women before IVF, as it helps to eliminate the negative effects of prolonged hormonal therapy and improves the blood supply to the pelvic organs. Reviews on the use of Wobenzym in gynecology are of interest to many.

Inflammatory diseases of the appendages and uterus are the most common pathologies in women. Therefore, the drug, which includes all inflammatory processes in the indications, is very popular among doctors. But, besides this, this drug is often prescribed as part of a complex treatment:

• urethritis - inflammatory processes of the urethra;
• thrombophlebitis and thrombosis;
• cystitis is an inflammatory process in the bladder;
• menopause;
• mastopathy.

Reviews of specialists about Wobenzyme in gynecology are also positive.

An important advantage of this drug is the obstacle to the transition of pathology from acute to chronic form. For this reason, it is often prescribed as monotherapy to prevent the recurrence of certain chronic pathologies.

Also in gynecology, the drug "Wobenzym" is used to prevent thrombosis. For example, it is prescribed to women who suffer from varicose veins and some other diseases of the circulatory system.

Instructions for use in gynecology

The course of taking this drug in gynecology is prescribed individually by the attending physician. The recommended dosage directly depends on the severity of the pathological process and its localization.

According to reviews, "Wobenzym" in gynecology has helped many women become pregnant.

Most often, for the treatment of acute forms of diseases, five tablets are prescribed three times a day. A similar course of therapy is two weeks.

For the treatment of the chronic form of the disease, the patient is prescribed to take five tablets three times a day for a month. After the active stage of therapy, to maintain the achieved result and restore the body, it is prescribed to drink three more tablets three times a day for 2-3 months.

Usually "Wobenzym" is prescribed together with antibiotics to reduce their negative impact on the body.

For the treatment of severe pathologies or a pronounced adhesive process, the drug is prescribed to be taken continuously for six months or a year.

Tablets should be taken on an empty stomach 30 minutes before a meal or a few hours after it. The drug must not be chewed.